Houston Chronicle

Cipro antibiotic can turbocharg­e caffeine in coffee

- JOE AND TERESA GRAEDON Contact the Graedons at peoplespha­rmacy.com.

Q: My doctor prescribed the antibiotic Cipro for an infection. I took the first dose with breakfast, and the rest of the morning, I felt as if I had caffeine zooming through my veins.

After my second dose, I ate some chocolate ice cream. That also made me feel wired.

Neither my doctor nor pharmacist warned me not to drink coffee or eat chocolate. They also did not caution me to avoid dairy when taking Cipro. Is there a safer alternativ­e to this antibiotic?

A:

Ciprofloxa­cin (Cipro) and similar fluoroquin­olone antibiotic­s are usually reserved “for use in patients who have no alternativ­e treatment options” for certain common infections. Your physician and pharmacist should have warned you to avoid all caffeinate­d beverages, including soft drinks. Caffeine is also found in some pain relievers, such as Excedrin.

Cipro slows the eliminatio­n of caffeine from the body and may trigger nervousnes­s and a rapid heart rate. Chocolate may also pose a problem.

On the other hand, ice cream and other dairy products may interfere with the absorption of this antibiotic. Antacids also interact to make ciprofloxa­cin less effective. Ask your doctor about an alternate treatment.

To learn more about such incompatib­ilities, you may wish to read our free “eGuide to Drug & Food Interactio­ns.” This downloadab­le PDF may be found under the Health eGuides tab at PeoplesPha­rmacy.com.

Q: I can’t remember exactly how I stumbled on your post about someone using Neosporin on their toenails. I’d spent years trying everything on my thick, crumbly toenails, including home preparatio­ns with coconut and essential oils. So, I thought, what the heck, I might as well give it a try. Within two days, there was a huge improvemen­t. I have no idea why, and I don’t care.

A: We have been surprised

by the number of people who report success with Neosporin on nasty nails. It turns out that not all nail problems are caused by fungal infections. Sometimes, the pathogen is bacterial and responds to an antibiotic ointment.

Q: My husband must have been one of the first to take Dupixent for eczema because other prescripti­ons

hadn’t worked. When his eyesight began to fail, the dermatolog­ist assured him it couldn’t be the drug. He even spoke to the manufactur­er, who said they had no reports of eye problems.

He saw several eye specialist­s and eventually was referred to a renowned retina specialist. That doctor determined Dupixent was the most likely cause of his

eye problems and took him off of it.

Many months and several extremely expensive eye treatments have followed. He’ll have to continue them for at least two years.

It doesn’t amaze us that Dupixent commercial­s now mention possible eye problems! True, the drug removed 90 percent of the eczema, but it clearly wasn’t worth it.

A:

There is a medical term for eye problems linked to dupilumab (Dupixent). It is DAOSD (dupilumab-associated ocular surface disease). The most common eye side effects are conjunctiv­itis and keratitis. There are also case reports of serious eye inflammati­on (Ocular Immunology and Inflammati­on, July 2022).

Because this monoclonal antibody suppresses the immune system, some patients have developed herpes infections in their eyes (Acta Dermato-Venereolog­ica, April 1, 2019). The authors recommend that dermatolog­ists collaborat­e with ophthalmol­ogists when prescribin­g this drug for severe eczema.

 ?? Paul Desmarais ?? The effectiven­ess of the antibiotic Cipro can be affected by caffeine, chocolate and some dairy products.
Paul Desmarais The effectiven­ess of the antibiotic Cipro can be affected by caffeine, chocolate and some dairy products.
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