Indianapolis-CarmelAnderson, IN

This Midwestern city is finally benefiting from some local successes: When Genesys bought Interactive Intelligence and Salesforce bought ExactTarget, a few of those founders stuck around and created new startups or venture capital firms. The arrival of Salesforce has been a boon for the city— not just for the promise of $40 million in investment but also for putting a major software company’s name on the city’s (and state’s) tallest building. This year, Indian outsourcing tech company Infosys also opened an office, with the promise of 2,000 jobs by 2021. With a low cost of living and world-class sporting and cultural institutions, it’s an attractive spot for Millennials, too.