American League

Redsox3,orioles1— At Boston, Andrew Benintendi and Mitch Moreland had three hits apiece to back Chris Sale, who held Baltimore to one run on two hits and struck out eight in five innings, as Boston (13-2) extended the best start in its 118-year history.

Athletics2,mariners1— At Seattle, Jed Lowrie hit a two-run homer in the first inning off Felix Hernandez (2-2), and Sean Manaea (2-2) held Seattle to one run on two hits over seven innings. Taylor Motter homered for the Mariners, who had won four straight. Harrison Bader hit a two-run homer to back Carlos Martinez (2-1), who blanked Cincinnati on two hits and struck out 11 in seven innings, handing the Reds their eighth straight loss and first four-game home sweep by St. Louis since 1949.

Padres 10, Giants 1 — At San Diego, Joey Lucchesi (2-0) held San Francisco to one run and struck out nine over six innings, fellow rookie Christian Villanueva homered, doubled and drove in three runs, and Jose Pirela was a home run short of the cycle and totaled three RBIS.

Rockies 6, Nationals 5 — At Washington, Ian Desmond hit a tiebreaking two-out homer in the ninth off Sean Doolittle (0-1), and Charlie Blackmon homered, doubled and drove in three runs for Colorado, which took three of four in the series.

Pirates 7, Marlins 3 — At Miami, Starling Marte went 5-for-5 with a ninthinning home run and scored four runs for Pittsburgh (11-4), which improved to 7-0 in day games and headed home atop the NL Central.