LIONS 26, CARDINALS 23 49ERS 36, GIANTS 9

Matt Prater made a 39-yard field goal as time expired, Matthew Stafford threw two touchdown passes and the visiting Lions snapped an 11-game losing streak dating to last season. The Lions looked like they would take the lead with about two minutes left when Stafford completed a spectacular deep pass to Marvin Hall at the 1-yard line, but the play was called back when offensive lineman Halapoulivaati Vaitai was flagged for holding. In the end, it didn’t matter. Stafford calmly led the Lions downfield, Prater connected on his fourth field goal of the afternoon and the Lions finally got to celebrate a victory. It was Prater’s 15th game-winning kick with less than 2 minutes to play in the fourth quarter or overtime. Arizona’s Kyler Murray threw for 270 yards and two touchdowns and ran for a score, but he also had three interceptions. Deandre Hopkins caught 10 passes for 137 yards and Andy Isabella had two TD receptions.

■ NEXT: Saints at Lions, 10 a.m. Sunday. Cardinals at Panthers, 10 a.m. Sunday.

Backup quarterback Nick

Mullens threw for 343 yards and a touchdown and the 49ers controlled the ball on offense, took it away on defense and had another easy day at Metlife Stadium. San Francisco played a near flawless game as Mullens hit 25 for 36 passes, including a 19-yard TD pass to running back Jeff Wilson. It outgained New York 420-231, held the ball for 39:44 and forced three turnovers without giving the ball up. The Giants did not run a play in the red zone. San Francisco scored on seven of its first eight possessions. It would have been all eight but a snap-hold problem led to Gould missing a 55-yarder. He connected from 52, 32 and 26 yards. The Niners’ ninth possession ended the game New York, which came into the game as the NFL’S lowest-scoring offense, got three field goals from Graham Gano, the second of which tied the game at 6-all midway through the second quarter. Quarterback Daniel Jones turned the ball over twice.

■ NEXT: Eagles at 49ers, 5:20 p.m. Sunday. Giants at Rams, 1:05 p.m. Sunday.