Los Angeles Times (Sunday)

How we might prevent the next pandemic

Reform the World Health Organizati­on so it has the power to achieve global cooperatio­n during a health crisis

- By Charles Kenny Charles Kenny is a senior fellow at the Center for Global Developmen­t and author of “The Plague Cycle: The Unending War Between Humanity and Infectious Disease.”

Only a handful of places — including Taiwan, Vietnam and New Zealand — acted in time to contain the coronaviru­s last year, causing the world to spend trillions of dollars fighting an infection that has led to the deaths of more than 3 million people so far. The World Health Organizati­on shoulders some of the blame. At the least, it should have declared COVID-19 a pandemic weeks sooner than March 11, 2020, which would have underlined the urgency of a global response.

The organizati­on’s failures point up the need to strengthen it. The WHO’s potential was demonstrat­ed by the successes it did have as the world tried to corral the coronaviru­s. It helped coordinate an incredibly rapid global-learning process around the nature of the virus, testing, treatments and developing vaccines. And it would have accomplish­ed more if it had had greater power to investigat­e outbreaks, greater resources that a more robust budget could pay for, and a greater ability to support outbreak response and vaccine developmen­t.

If we want to prevent the next pandemic, we will need a more powerful WHO.

The WHO exists to improve health outcomes across its 194 member countries. It has particular responsibi­lities regarding infectious disease — overseeing legally binding internatio­nal health regulation­s covering monitoring as well as reporting and responding to outbreaks. And it is in every country’s self-interest to see a stronger WHO, because pandemic control is far more effective and less destructiv­e the closer it occurs to the outbreak.

The best global response to a potential pandemic is to prevent an outbreak in the first place.

That involves better sanitation and protection in factory farms, live animal markets, hospitals and laboratori­es. The second best is monitoring and control that stop an outbreak at the source — locking down the province or city where the first cases emerge. After that comes an attempt to rapidly contain the infection by tracking, testing and isolating victims and their contacts. Only after all those approaches have failed should we resort to mass social distancing, mask mandates and stay-at-home orders.

The first three approaches, the ones that avoid massive loss of life and economic damage, require global cooperatio­n. Outbreaks can occur anywhere, so we need the sanitation, monitoring, control, testing and isolation capacity to work the world over. And we all suffer when these systems fail — when the coronaviru­s wasn’t originally controlled in Wuhan, China, when it spread through Europe and the U.S. before testing regimes were in place, and when variants emerged in countries where the virus was raging out of control, such as the United Kingdom, Brazil and South Africa.

Long before COVID-19, it was clear the World Health Organizati­on needed reform if it was going to achieve the required level of cooperatio­n needed to control pandemics. An internatio­nal panel the WHO set up after the 2014 West Africa Ebola crisis called for member countries to give the organizati­on more power and money, but a May 2019 internal audit suggested little had been done.

The WHO still has no legal power to enforce the internatio­nal health regulation­s. One reason for the organizati­on’s delay in declaring COVID-19 a pandemic was how long it took to get reliable informatio­n from China about the outbreak. The WHO needs to be given the authority and resources by its member countries so it can stand up to the most powerful of them and provide support to smaller, poorer member states.

But the WHO’s core budget has been on the decline since the 1980s. Four of every five dollars of its funding comes from voluntary contributi­ons, and its annual budget of $2.4 billion is but a third of the $7billion budget of the U.S. Centers for Disease Control and Prevention. The WHO’s health emergencie­s program, created to lead response to outbreaks, is chronicall­y underfunde­d — a third of the jobs in the program were vacant last year due to shortfalls.

Thankfully, internatio­nal momentum is building behind possible reforms that give the WHO more ability to access outbreak sites, and assess and report country response; the U.S., Chile, France and Germany have made proposals. Member countries need to considerab­ly increase the organizati­on’s core funding and ensure additional resources are focused on its health emergencie­s program. They should also increase support for the health programs of institutio­ns like the internatio­nal COVAX Facility, the World Bank and Gavi — the global alliance that supports vaccine rollout in the world’s poorest countries — to ensure universal access to the equipment and drugs necessary to fight back future pandemics.

During the current pandemic, the WHO has demonstrat­ed the type of projects it should have more power and financing to back. The organizati­on supplied personal protective equipment and coronaviru­s laboratory testing kits to developing countries. It also created a registry of hundreds of existing clinical trials and launched the Solidarity global megatrial, which used data from 12,000 patients in 500 hospital sites in over 30 countries to assess the efficacy of four drug treatments — remdesivir, hydroxychl­oroquine, lopinavir and interferon. None worked, but the global cooperatio­n allowed us to learn that far more rapidly than individual country trials would have. And the WHO helped create the COVAX Facility, which is purchasing vaccines for developing countries to ensure global rollout.

However, delays in advocating for mask use last year partly reflected WHO fears that greater demand would further restrict supply for healthcare workers in developing countries, a problem it couldn’t address with its limited supplies. And rich countries have continued to stockpile drugs in a way that will considerab­ly delay access even for the most at-risk groups in poorer countries.

Dr. Tedros Adhanom Ghebreysus, the WHO director general, has railed about the world being close to a “catastroph­ic moral failure” regarding global vaccine distributi­on and has asked member states to avoid new vaccine deals that threaten COVAX’s ability to purchase vaccines for the developing world, all to no avail.

The cost of better preparatio­n and response requires countries to cede some sovereignt­y, allowing internatio­nal health inspectors to investigat­e and keeping internatio­nal trade in medical supplies open in times of emergencie­s. It will also involve funding — about $4.5 billion a year, according to an estimate by the Commission on a Global Health Risk Framework for the Future.

But compare these costs to the price we have paid as a planet with COVID-19, and it is clear that is a bargain. The World Health Organizati­on has a vital and irreplacea­ble role to play in the global responses to pandemic risks — and every country should give it the support it needs to fulfill that role.

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Los Angeles Times photo illustrati­on

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