Los Angeles Times

VA superbug exposure probe

Officials say patients could have been exposed to superbug from tainted scopes.

- By Chad Terhune chad.terhune@latimes.com

Officials say patients could have been exposed to a deadly superbug from tainted medical scopes.

Veterans Affairs Department officials are investigat­ing whether patients have been exposed to antibiotic­resistant superbugs from tainted medical scopes in the wake of several hospital outbreaks.

The VA said Friday that it began looking into the possibilit­y of patient infections in late February after a deadly outbreak was disclosed at UCLA’s Ronald Reagan Medical Center.

“We are investigat­ing whether anyone has been infected with antibiotic-resistant bacteria linked to the use of these scopes,” VA spokeswoma­n Ndidi Mojay said. “The results of the investigat­ion haven’t come back yet.”

As part of the government review, the VA’s National Program Office for Sterile Processing has been in contact with manufactur­ers of the devices, known as duodenosco­pes, “to ensure every effort has been made toward addressing the current issue of a drug-resistant superbug known as CRE, or carbapenem-resistant Enterobact­eriaceae.”

CRE is highly resistant to antibiotic­s and can kill up to 50% of infected patients.

Seven UCLA patients were infected with CRE from contaminat­ed scopes, including two who later died. The scopes are used in a procedure called endoscopic retrograde cholangiop­ancreatogr­aphy, or ERCP.

Last week, Cedars-Sinai Medical Center disclosed that four of its ERCP patients were infected with CRE, and it notified more than 60 other patients about possible exposure.

Last month, federal authoritie­s warned hospitals about the difficulty in cleaning the complex scopes and how bacteria can become trapped in tiny crevices at the tip of the devices.

The VA said it “enforces strict adherence to manufactur­er instructio­ns … for pre-cleaning at the bedside, manual cleaning in the decontamin­ation area as well as high-level disinfecti­on.”

VA officials said they also take additional steps to ensure patient safety, from rigorous employee training to routine testing of scopes after cleaning to check for dangerous germs that may have been missed.

In 2009, the VA discovered a similar problem with endoscopes used for colonoscop­ies. At that time, the agency notified about 11,000 patients that they may have been exposed to HIV, hepatitis C and other diseases because endoscopes weren’t properly cleaned and became contaminat­ed.

The VA health system includes more than 150 medical centers and nearly 1,400 outpatient clinics across the country.

When it comes to the deadly CRE superbug, patients can become infected in a number of different ways or bring it with them into the hospital in some cases. Many hospitals have increased surveillan­ce and testing of patients to better determine the source after the recent incidents.

On Thursday, the Centers for Disease Control and Prevention issued recommenda­tions for how hospitals can test their duodenosco­pes.

Some hospitals have started to quarantine their scopes for up to 48 hours after cleaning to culture them for any bacterial growth before reuse. However, that can require purchasing many more scopes, which can cost up to $40,000 apiece.

Other hospitals are considerin­g weekly scope testing or turning to gas sterilizat­ion of the instrument­s to kill off harmful bacteria.

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