Los Angeles Times

Coronaviru­s threat grows in the Southland, Central Valley

With 6,000 cases in L.A. County, chances of exposure rising rapidly

- By Rong-Gong Lin II, Ryan Menezes, Sean Greene and Joe Mozingo

The San Francisco Bay Area suffered one of the nation’s earliest outbreaks of COVID-19, but cases from Southern California and the Central Valley are outpacing it, threatenin­g a much larger population, according to a Times analysis of county health data.

Los Angeles, San Diego, Riverside, San Bernardino, Kern, Stanislaus and Tulare counties are now seeing faster rates of newly detected coronaviru­s cases than any of the counties in the Bay Area, the Times analysis found.

And with more than 6,000 confirmed cases in L.A. County alone, chances of exposure are increasing rapidly.

“If you have enough supplies in your home, this would be the week to skip shopping altogether,” L.A. County Public Health Director Barbara Ferrer said Monday.

“Without everyone taking every possible precaution, our numbers can start skyrocketi­ng,” she said. “It really is time for those people who maybe haven’t taken this seriously before ... this would be the week to stay home ... and it may be next week as well.”

While California has yet to see the worst of the pandemic, there were signs that some of the more dire prediction­s might not come to fruition.

Gov. Gavin Newsom, who has tried to prepare the state for the worst-case scenario, said California had enough ventilator­s to lend 500 to the Strategic National Stockpile to help New York and other COVID-19 hot spots facing shortages of the desperatel­y needed medical devices.

“We want to extend not only thoughts and prayers, but we’re also extending a hand of support with ventilator­s,” Newsom said during a news briefing Monday in Sacramento.

Newsom said lending the ventilator­s was possible because hospitals throughout California have procured

thousands of them in the last few weeks, increasing their ventilator inventory from 7,587 to 11,036.

Also Monday, the inf luential Institute for Health Metrics and Evaluation, an independen­t population health research center at the University of Washington, predicted a significan­tly lower death count in California than its earlier models, based on new data from Spain and Italy.

On March 26, the center forecast 6,109 deaths in California during this outbreak, a number seen by many at the time as overly optimistic.

On Monday, the institute reduced that projection to 1,783, with a range of uncertaint­y of 1,400 to 2,400 and the last death occurring on May 20.

The peak in patients is forecast to roll through hospitals on April 15, and the worst day for fatalities two days later, with 70 deaths.

The numbers changed largely because seven locations in Italy and Spain “appear to have reached the peak number of daily deaths,” the researcher­s wrote in their update. They no longer had to rely solely on data from Wuhan, China.

“The time from implementa­tion of social distancing to the peak of the epidemic in the Italy and Spain location is shorter than what was observed in Wuhan,” they wrote. “As a result, in several states in the

U.S., today’s updates show an earlier predicted date of peak daily deaths, even though at the national level the change is not very pronounced.”

New data also changed how the team weighed the effects of different social distancing factors — closed schools, stay-at-home orders, shutting down nonessenti­al businesses — in its calculatio­ns.

The researcher­s’ model projects that the last death from the virus in the United States will occur on June 22 and that the nation’s total death toll will be 81,766, within a range of uncertaint­y of 49,431 to 136,401.

The states expected to be hit hardest: New York, 15,618 deaths; New Jersey, 9,690; Massachuse­tts, 8,254; and Florida, 6,770.

Epidemiolo­gists have questioned the reliabilit­y of any prediction model, given the number of uncertaint­ies plugged into the algorithms — erratic human behavior, spotty testing, possible underrepor­ting of deaths.

“When you multiply uncertaint­y with uncertaint­y, you get larger uncertaint­y,” said Dr. Loren Miller, a physician and infectious diseases researcher at the

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. “And that’s where models are limited. They can make guesses about what will happen, but they can be way off in either direction. Too optimistic or too pessimisti­c.”

Other models have projected far bleaker statistics. And critics of the University of Washington model have expressed fears that the Trump administra­tion relies on it too heavily because it paints a brighter picture than others.

And all this could be just the first wave of the COVID-19 pandemic. Others could follow in weeks, months or years.

California state officials expect that the peak of this outbreak will not be reached until mid-May and high infection rates could last into summer.

The number of new cases in L.A. County has been rising steadily, with the number of daily new cases increasing from about 300 a week ago to between 422 and 720 in the last several days.

While the rate of growth slows near the peak, the sheer numbers get bigger every day. Doubling 10 cases in a single day is a high rate of growth. Doubling 6,000 cases in five days is a much slower rate of growth — with a much bigger impact.

Cases in Los Angeles, Riverside, San Bernardino and San Diego counties are now taking about four to five days to double, while Alameda, Contra Costa, San Mateo and Solano are taking six to seven.

The pace is slowing down even more in San Francisco, where the doubling time is every 10 days, and in the original epicenter of California’s outbreak, Santa Clara County, where the doubling time is now every 11 days. In mid-March, that was happening every four days.

Los Angeles County saw its fastest rate of coronaviru­s cases in late March, when it was taking just about every two days for coronaviru­s cases to double, the Times analysis found.

The Inland Empire is seeing a sharp rise in infections, with San Bernardino County reporting 157 new cases Monday, for a total of 530, a 42% jump.

Part of the reason for the faster pace of coronaviru­s cases in Southern California could stem from the Bay Area acting earlier to implement a stay-at-home order, said Dr. George Rutherford, an epidemiolo­gist and infectious diseases expert at UC San Francisco.

The Bay Area shocked the nation on March 16 when it was the first region in the nation to announce a shelter-in-place policy ordering residents to stay at home as much as possible.

The measures extended to Southern California on March 19, when Newsom announced a statewide stayat-home order on the same night Mayor Eric Garcetti issued his own for the city of Los Angeles.

Case counts can be problemati­c in tracking the course of this coronaviru­s outbreak, given the limited availabili­ty of testing.

But they can still be helpful because they also translate to how many people are being seen in the hospitals to be treated for COVID-19, “so they’re reasonably accurate, and I don’t think there’s any big differenti­al between Northern and Southern California in terms of ease of obtaining tests,” Rutherford said.

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