Los Angeles Times

A second-class vaccine?

Some are worried that Johnson & Johnson shot is less effective and will be pushed into poor areas

- ERIKA D. SMITH

After weeks of being talked up and fawned over by public health officials, the new COVID-19 vaccine from Johnson & Johnson is finally starting to make an appearance in California.

In most quarters, this has been a cause for celebratio­n. Hundreds of thousands of doses that don’t have to be stored in freezers and can be administer­ed in one dose instead of the two required for the Pfizer and Moderna vaccines? No wonder I’ve heard several politician­s call it a “game changer,” especially after so many months of supply shortages.

But in other quarters, the arrival of the Johnson & Johnson vaccine has been treated more as a cause for concern — yet another reminder that having doses available and actually getting them into people’s arms in an equitable way are two very different challenges

to overcome.

At issue are fears about the effectiven­ess of the newest vaccine compared with offerings from Pfizer and Moderna, and suspicions that it will be sent primarily into poor Black and Latino neighborho­ods where COVID cases have been deadliest. State and federal officials have insisted they will take steps to ensure this doesn’t happen.

“That they are going to put Johnson & Johnson in our communitie­s really feels like a slap in the face,” said Corey Matthews, chief operating officer of Community Coalition. “It just doesn’t feel like it is the best shot. It feels like a second-class shot.”

Meanwhile, the messaging from public health officials has been consistent: Take whatever vaccine is offered. All three will save your life and prevent you from ending up on a ventilator. The brand doesn’t matter and neither do the efficacy ratings. The vaccines are basically the same.

Matthews, who has been going door to door, booking appointmen­ts for people in South L.A. who otherwise probably wouldn’t know how to get vaccinated, is skeptical that such messaging will work on a population marginaliz­ed by systemic racism and distrustfu­l of government institutio­ns.

Persuading people to set aside their hesitancy and get immunized has required educating them about the Moderna and Pfizer vaccines, Matthews said, and adding a new one to the mix could undermine progress. People “don’t know what

Johnson & Johnson is,” he said, and so won’t get it.

Then there’s confusion over efficacy ratings. The Johnson & Johnson vaccine had a lower rating than the other two vaccines at preventing symptomati­c COVID-19 infections. But it’s also not that simple. All three vaccines were tested in different clinical trials in different conditions and never head-to-head, so a direct comparison of the sort everyone wants to make is actually impossible.

“You’re already talking about hard-to-access, hardto-reach communitie­s,” Matthews said. “And now we’re going to basically undercut the little bit of progress that we’ve made.”

Detroit Mayor Mike Duggan was even more blunt when he initially turned down doses of the new vaccine for his constituen­ts. “Johnson & Johnson is a very good vaccine. Moderna and Pfizer are the best,” he said. “And I am going to do everything I can to make sure the residents of the city of Detroit get the best.”

Many of those working on the front lines feel the same way about Los Angeles. But many others don’t see Johnson & Johnson as a lesser option, and instead see the debate over its rollout as a distractio­n from the far more important work of getting doses into arms.

I spoke with several elected officials, whose districts crisscross South Los Angeles, and they all downplayed such concerns or said they hadn’t heard anyone voice them. Mayor Eric Garcetti also defended the new vaccine during a recent Zoom event for Black Angelenos about COVID-19.

“Johnson & Johnson — it’s not a secondary vaccinatio­n. It’s as good as the other two,” he said, seemingly in response to a question that no one had asked. “In fact, I know a lot of people just want to get one shot and be done because it’s 100% effective at keeping you from dying and being hospitaliz­ed. That’s clear.”

The dueling narratives — one based on fact, the other based on fear — illustrate what the White House has been trying to avoid since the Food and Drug Administra­tion first authorized the Johnson & Johnson vaccine for emergency use in late February.

Dr. Marcella NunezSmith, who’s leading the Biden administra­tion’s work on health equity and the coronaviru­s, said last week that all three vaccines will be distribute­d evenly and that if certain vaccines consistent­ly end up in certain communitie­s, “we will be able to intervene.”

California’s Health and Human Services Secretary Dr. Mark Ghaly has said much the same, though it could prove somewhat more difficult to do, given that the rollout of the Johnson & Johnson vaccine happens to coincide with Gov. Gavin Newsom’s decision to reserve 40% of California’s supply of COVID-19 vaccines for the state’s poorest residents.

This doesn’t mean that the state will be flooding sites in Black and Latino neighborho­ods with doses of the Johnson & Johnson vaccine — at least any more than it will be with doses of the Pfizer and Moderna vaccines. But, in the name of equity, it may look like it.

There’s also a logistical reason that poor neighborho­ods should get more than their share of the new vaccine, given that it doesn’t need to be kept as cold and is therefore easier to administer door-to-door in neighborho­ods where people don’t have cars or are otherwise homebound. The oneshot formula also is ideal for vaccinatin­g essential workers with multiple jobs and little free time or for people who are homeless or otherwise difficult to track down for second doses.

The Johnson & Johnson vaccine really can be a game changer. It has the potential to save a lot of lives. But getting California­ns to take it means public health officials first need to get serious about nixing the narrative that it’s somehow secondclas­s.

Just saying that all the vaccines are the same isn’t going to cut it — not after public health officials spent months touting the northof-90% efficacy ratings for the Moderna and Pfizer vaccines as a way to persuade hesitant Americans to roll up their sleeves for the needle.

Nor does telling people not to pay attention to brands. This is America, after all. During my last stint as a volunteer at Kedren Community Health Center, which is now offering both the Pfizer and Moderna vaccines, I lost track of how many people requested a specific brand and wanted to argue when they were told no. Who knows what will happen when doses of Johnson & Johnson show up.

“Get the first vaccine that’s offered” is sound advice. But let’s not forget to explain why.

 ?? Michael Ciaglo Getty Images ?? THE ONE-DOSE Johnson & Johnson vaccine has been celebrated by health officials and politician­s. But many harbor concerns that it’s less effective.
Michael Ciaglo Getty Images THE ONE-DOSE Johnson & Johnson vaccine has been celebrated by health officials and politician­s. But many harbor concerns that it’s less effective.
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 ?? David Zalubowski Associated Press ?? THOUGH experts are stressing that all available vaccines are effective, some see the new Johnson & Johnson shot as second-class. Above, medical staff draw doses of the vaccine at the National Jewish Hospital in Denver.
David Zalubowski Associated Press THOUGH experts are stressing that all available vaccines are effective, some see the new Johnson & Johnson shot as second-class. Above, medical staff draw doses of the vaccine at the National Jewish Hospital in Denver.

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