Los Angeles Times

Uneven uptake of pediatric vaccine

- By Luke Money and Rong-Gong Lin II

Early demand for the COVID-19 vaccine for young children has been startlingl­y uneven in California, with some areas embracing the shots and others much slower to accept them, a Times data analysis has found.

It’s a pattern that has experts concerned and could have serious implicatio­ns for how a coronaviru­s winter surge could spread through various regions of the state.

In San Francisco, 30% of 5- to 11-year-olds have received one shot since the vaccinatio­n was authorized for the age group three weeks ago. In Santa Clara County, home to Silicon Valley, the figure is 28%, and in Marin County, once a hotbed of antivaccin­ation sentiment, it’s an astonishin­g 46%, according to a Times analysis of state data.

Those rates are well above the national rate of 12% and the statewide rate of 13%.

Los Angeles and Orange counties are reporting that 12% of kids in the age group are partially vaccinated; San Diego County reports 13%, and Ventura County, 10%.

Yet uptake of vaccines for kids is lagging across inland California, with rates of 5% in San Bernardino and Kern counties, 6% in

Riverside County and 7 %in Fresno County.

“In one sense, the higher levels of 5- to11 -year-old vaccinatio­n rates is somewhat as urrogate measure for vaccine acceptance at all ages,” said UCLA epidemiolo­gist Dr. Robert Kim-Farley.

Generally, the areas of California with the slowest rate of administer­ing vaccines — rural Northern California and the Central Valley — are where COVID-19 hospitaliz­ation rates are the highest.

“There will be a winter surge,” said UC San Francisco epidemiolo­gist Dr. George Rutherford. “What I worry about most is the Central Valley, in more rural California, where vaccinatio­n rates are lower than they are in other parts of the state and are currently having high levels of transmissi­on.”

The outlook is most optimistic for the San Francisco Bay Area, which has the state’s highest vaccinatio­n rate and lowest COVID-19 hospitaliz­ation rate.

“In parts of California with higher vaccinatio­n rates ,I think we can fully expect the winter surge to be more blunted. W emaya void it; we may not. I suspect it will just be at a lower level,” Rutherford said.

The future for the coastal Southern California counties is less clear.

It’s possible that the level of vaccinatio­n, plus naturally acquired immunity from last winter’ ss urge, will leav eSo uthern California’s biggest metro areas “reasonably protected,” Rutherford said.

I nadi verse area like Los Angeles County, there will likely be varying rates of COVID-1 9v accination­s, according to Dr. Kirsten Bibbins-Domingo, chair of UC San Francisco’s Department of Epidemiolo­gy and Biostatist­ics.

“Ultimately, the experience of vaccinatio­n rates is very local. And so how it will play out — it might be some average of the two extremes in the Bay Area and the San Joaquin Valley , bu t probably more [likely] it will be that some communitie­s will really b em uch more protected, and some will have the potential to have strikingly higher rates of transmissi­on, especially as we get to the holidays,” BibbinsDom­ingo said.

The Inland Empire is already suffering from significan­tly worse COVID-19 hospitaliz­ation rates than coastal Southern California counties.

Riverside County has double the COVID-19 hospitaliz­ation rate of L.A. County, while San Bernardino County has triple the rate. In San Bernardino, the daily patient count has swelled b ya bou t3 4% since mid-October.

In San Bernardino and Riverside counties, fewer than 55% of residents of all ages are fully vaccinated, compared with roughly 65% in L.A. and Orange counties and more than 75% in several Bay Area counties.

“They are much worse positioned going into the winter and holiday seasons because of their relatively lower vaccinatio­n coverage rates — not only in 5- to 11year-olds, but in all age groups ,”K im-Farley said.

Infected children can be significan­t players in the spread of the Delta variant of the coronaviru­s.

Recently, 5- to 11-yearolds have, at times, had the highest coronaviru­s case rates among all pediatric groups in Los Angeles and Orange counties.

Young children are not only at risk of becoming sick themselves but can pass the virus to older relatives, who — even if they are fully vaccinated — would be at higher risk of suffering severe illness should they get a breakthrou­gh infection.

Nationally, new weekly coronaviru­s cases among children of all ages hav e increased b ya bou t3 2% since the beginning of the month, resulting in more than 140,000 children with confirmed infections for the seven-day period that ended Thursday, according to an analysis by the American Academy of Pediatrics and Children’s Hospital Assn. Children now represent 25% of the nation’s reported new cases.

While some people have noted that children are less likely to suffer severe illness from COVID-19 than adults, it remains crucial that they get vaccinated, epidemiolo­gists say.

The numb er of 5 - to 11year-olds who died from COVID-19 in a one-year period — 66 — makes the disease equivalent to the eighth leading cause of death for that age range.

Some physicians also worry about possible longterm consequenc­es of COVID-19 in children, such as higher rates of depression or anxiety, difficulty concentrat­ing in school or longterm headaches. Children also have a rare risk of developing a multisyste­m inflammato­ry syndrome related to COVID-19 that can result in serious illness and death.

“Getting children vaccinated is an important part of increasing the overall vaccinatio­n coverage and limiting transmissi­on,” Rutherford said. “High vaccinatio­n equals low transmissi­on. Low vaccinatio­n begets high transmissi­on.”

Officials need to recognize that it’s likely more difficult for people in low-income communitie­s to get access to pediatric COVID-19 vaccines, Bibbins-Domingo said.

“When you look in the Central Valley ,I worry about both active hesitancy as well as, do we have the resources to reach all of the communitie­s in those areas? ... How effective are we at getting vaccines to all the communitie­s where we need to?” she said.

L.A. County officials are concerned that Black and Latino 5- to 11-year-olds and those in that age group from lower-income households have been less likely to get vaccinated.

The L.A. County Department of Public Health said Tuesday that white children were three times more likely than Black and Latino children to get vaccinated. While 13% of white, 14% of Asian American and 12 %of Native American children in the age grou pha ve received a shot, just 4% of Black and 3% of Latino children had done so by Nov .1 4.

Children in this age grou pli ving in the neediest neighborho­ods are being vaccinated at one-third the rate of those in wealthier communitie­s: 3.9% versus 12.5%.

“If we continue to see disparitie­s in pediatric vaccinatio­n that put Black and Latinx children at higher risk when transmissi­on increases, we could once again see a situation where these communitie­s suffer the most during a surge,” L.A. County Public Health Director Barbara Ferrer said in a statement Tuesday.

Last week, Ferrer said the disparitie­s in vaccinatio­ns demonstrat­e a need to “build trust in the safety and efficacy of the pediatric vaccine by ensuring that parents have good informatio­n, are getting their questions answered and know where to go to get their child vaccinated,” Ferrer said.

Ferrer said L.A. County is working to improve access to vaccines for children in areas where it has been difficult. As of last week, there were more than 700 sites countywide administer­ing doses to 5- to 11-year-olds; hundreds more are expected to begin doing so in the coming weeks.

There’s good reason many experts expect a winter surge to hit California.

Nationally, new daily coronaviru­s cases have risen b y3 0 %o ver the past month, from about 72,000 to 94,000; COVID-19 hospitaliz­ations have risen b y 15% o ver the past two weeks.

The U.S. Centers for Disease Control and Prevention considers California to have “substantia­l” community transmissi­on, the secondwors­t category in its fourstep scale.

California saw both its weekly case rate and hospitaliz­ation rate increase in late October; however, in the past two weeks ,b oth numbers have declined.

Still, the state has leveled off at a relatively high rate. The number of daily cases being reported is more than four times higher than in mid-June, when the state reopened its economy and lifted most pandemic-related restrictio­ns on public spaces. COVID-19 hospitaliz­ations are now three times higher than what the state was experienci­ng at that point.

Warning signs are also apparent in other states, where the coronaviru s is once again on the rampage. California’ so verall rate of full vaccinatio­n is about the same as those of Colorado, Minnesota and New Mexico, which are all experienci­ng surges and crowding in hospitals.

“Our 63%, while it’s great, isn’t enough,” Rutherford said of California’s vaccinatio­n rate.

In Fresno County, hospitals are consistent­ly operating above capacity, and ambulances are being forced to idle outside hospitals before they can unload patients into packed emergency rooms.

“We don’ t ha ve enough hospitals to serve the population and the needs,” said Dr. Rais Vohra, the Fresno County interim health officer.

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