Los Angeles Times

Don’t let Adderall scarcity trigger a crisis

Unless the U.S. boosts supply, many who lose access may turn to readily available alternativ­es like meth

- By Leo Beletsky Leo Beletsky is a professor of law and health sciences at Northeaste­rn University and faculty director of the Health in Justice Action Lab.

U.S. pharmacies are critically low on Adderall and its generic analogues, leaving more than 26 million patients scrambling and competing for the pills since late summer. The scarcity is going to last for many more months because of supply chain problems as well as federal restrictio­ns on manufactur­ers and imports.

If we don’t act fast, this shortage could trigger two major public health crises.

Many people who have been taking this amphetamin­e-based stimulant — whether prescribed for attention deficit or narcolepsy or used illicitly as a performanc­e or party drug — will lose access. This carries serious physical and mental health risks.

Amphetamin­e withdrawal symptoms, including depression, are not easily addressed with other kinds of drugs. So as countless individual­s are confrontin­g having to rapidly taper or stop, we’re facing a real possibilit­y of a public health disaster on a scale not seen since the prescripti­on opioid crisis that began a decade ago.

Instead of enduring withdrawal, other individual­s cut off from Adderall are likely to turn to alternativ­e stimulants like crystal meth, fueling a much broader crisis.

The early 2010s taught us that dependence and addiction don’t simply disappear when the pills do. At that time, catastroph­ic regulation failures contribute­d to widespread opioid dependence and addiction. The government response to the prescripti­on opioid crisis focused on rapidly reducing supply: crackdowns on pill mills, tightened restrictio­ns on prescribin­g and reformulat­ion of products to make them harder to snort and inject. This approach backfired, pushing many users onto the illicit market.

As a chemical analog of prescripti­on opioids, heroin was widely available and far cheaper than its pharmaceut­ical cousins. But its unpredicta­ble quality and link with injection drug use made heroin a much more dangerous alternativ­e; the recent rise in fentanyl contaminat­ion has further fueled the crisis. Overdose rates have continued to soar, spiking from 16,000 during the height of the prescripti­on opioid crisis to more than 100,000 annually. The number of cases of blood-borne infections like HIV and hepatitis has spiked in tandem.

Today’s Adderall shortage is setting up a similar crisis. For those losing adequate access to prescripti­on amphetamin­e, illicit alternativ­es — especially methamphet­amine — are readily available. Just as with heroin, years of increasing­ly punitive policies, aggressive law enforcemen­t, government fearmonger­ing and growing public panic failed to address the “meth problem.”

If anything, interventi­ons like the Combat Methamphet­amine Epidemic Act of 2005 disrupted meth production by a domestic cottage industry, cementing its reorganiza­tion as an internatio­nal, industrial operation — dramatized in the narrative arc of “Breaking Bad.” This made meth more ubiquitous, more potent and cheaper than ever.

Crisis events and cardiac arrests involving stimulants are already at an all-time high. Methamphet­amine injection is helping to drive infectious disease cases. And there are also concerns about street stimulants, including counterfei­t pills, being contaminat­ed with fentanyl, creating the risk of opioid overdose.

Enter the Adderall shortage.

A massive influx of people forced to switch from a pharmaceut­ical amphetamin­e to street methamphet­amine would be nothing short of a nightmare. But there is still time to prevent a stimulant remake of the tragedy we have seen play out with opioids.

The Food and Drug Administra­tion has powerful tools at its disposal to ease the Adderall shortage. This includes attracting and fast-tracking approval for internatio­nal manufactur­ers and helping rapidly develop domestic production.

Maintainin­g a reliable, safe supply of amphetamin­e medication­s is crucial to avoid a major public health crisis. Bigger thinking is also vital to prevent other similar crises from occurring in the future.

The current Adderall shortage is a symptom of deep structural dysfunctio­n in our institutio­ns, policies and systems responsibl­e for drugs. As with opioids, stewardshi­p of prescripti­on stimulants in American healthcare is poor, often vacillatin­g between excess and deficit. We need far more nuanced, patient-centered approaches to medication access that are not bogged down in drug panics and concerns about law enforcemen­t.

Meanwhile, our streets are flooded with illicitly manufactur­ed alternativ­es of unpredicta­ble content and dosage, despite cavalier investment­s in criminal justice efforts to stem their supply. Instead, cost-effective lasting solutions like housing, social services and wrap-around supports are necessary to make our society healthier and safer.

Bold actions are urgently needed to prevent history from repeating itself.

 ?? JB Reed Bloomberg ?? STIMULANTS like Adderall are widely prescribed and relied upon by millions.
JB Reed Bloomberg STIMULANTS like Adderall are widely prescribed and relied upon by millions.

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