Los Angeles Times

Mexican pharmacies sell fentanyl-, meth-tainted pills

Fake medication­s are passed off as legitimate in tourist areas

- By Keri Blakinger and Connor Sheets

CABO SAN LUCAS, Mexico — If you walk down the right side street, the offers are plentiful, even in broad daylight. Young men in plain T-shirts draw near and call out their wares: Pills. Cocaine. Guns.

But if you wave them away and go just a few feet farther, you can walk into a pharmacy where you might get something just as dangerous. You just won’t know it.

A Los Angeles Times investigat­ion has found that pharmacies in several northweste­rn Mexican cities are selling counterfei­t prescripti­on pills laced with stronger and deadlier drugs and passing them off as legitimate pharmaceut­icals.

In Tijuana, reporters found that pills sold as oxycodone tested positive for fentanyl, and pills sold as Adderall tested positive for methamphet­amine. Testing conducted farther south in Cabo San Lucas and

nearby San José del Cabo bore similar results, although there, even weaker painkiller­s — including pills sold as hydrocodon­e — also tested positive for fentanyl. Many are nearly indistingu­ishable from their legitimate counterpar­ts.

In total, the Times investigat­ion found that 71% of the 17 pills tested came up positive for more powerful drugs.

A team led by UCLA researcher­s recorded similar results in a study last week, but this phenomenon has otherwise gone largely unnoticed. The new findings could represent a dangerous shift in the fentanyl crisis.

Until now, it was unclear that the powerful synthetic opioid had made its way into pharmacy supply chains. Even though Mexican drugstores are known for selling a wide range of medication­s over the counter — many of which require a prescripti­on in the United States — experts generally believed those pills were at least what store owners said they were.

Now, that’s no longer a safe bet. “Whenever you have counterfei­t products that contain fentanyl, you are going to have people use them and die,” said Chelsea Shover, a UCLA researcher and the study’s senior author.

That’s because consumers — including U.S. tourists — who unknowingl­y buy these adulterate­d pills are at a higher risk of overdose when they ingest drugs far stronger than what they’re expecting. But how often that happens is impossible to tell.

Experts who study the effects of illicit drugs in Mexico say the country’s mortality data vastly undercount overdose deaths, which makes it difficult to understand the scope of the problem. While more than 91,000 people died of overdoses in the U.S. in 2020, Mexico reported just 1,700 fatalities that year from all drugs, including alcohol.

Fewer than two dozen of those, according to the data, were from opioids, compared with more than 68,000 opioid overdose deaths in the U.S. that year.

It’s unclear whether authoritie­s in either country are aware of the problem. Carlos Briano, a spokespers­on for the U.S. Drug Enforcemen­t Administra­tion, said in a statement, “We refer you to Mexican authoritie­s on this issue.”

The U.S. State Department and the White House’s Office of National Drug Control Policy did not comment in response to detailed phone and email inquiries. Multiple local and national government agencies in Mexico also ignored requests for comment.

U.S. Rep. David Trone (D-Md.), who co-chaired the U.S. Commission on Combating Synthetic Opioid Traffickin­g, called the findings of the Times investigat­ion “extremely concerning” in a statement.

State Sen. John Laird (D-Santa Cruz) described the findings as “really shocking.” Last year, he sponsored legislatio­n that made it easier for California pharmacies to distribute any new opioid reversal agents as soon as they are federally approved.

“These places are close at hand, and Americans travel to these locations, and they are at risk in a way that wasn’t apparent before,” Laird said. “And I think that as this story comes out and we learn further details we’re going to have to look to see if there’s any state legislatio­n that needs to be looked at to follow up.”

Fentanyl has been infiltrati­ng the illicit drug supply for roughly a decade, since trafficker­s seized on the synthetic drug as a cheaper alternativ­e to traditiona­l opiates — and one with a higher profit margin.

The U.S. Centers for Disease Control and Prevention has described fentanyl as up to 50 times stronger than heroin. A dose as small as 2 milligrams can be fatal. Unlike heroin, making it doesn’t require the space or expense of a sprawling poppy field — only a lab and the right chemicals.

When the drug first appeared on the street, it was often mixed into illicit powders. Then, it began appearing in counterfei­t pills made to look like the real thing. Getting one of those pills still required a willingnes­s to engage in illicit street deals.

But to many users, the faux pharmaceut­icals seemed safer than drugs that required shooting or snorting. Accordingl­y, street pills found a much larger market than powders. If those pills can now be purchased in legitimate pharmacies, that market becomes larger still.

Of the 10 drug experts reporters interviewe­d for this story, all but one said they’d never heard of pharmacies selling counterfei­t pills.

“I haven’t seen anything like that,” said Cecilia Farfán-Mendez, who studies cartels as head of research at UC San Diego’s Center of U.S.-Mexican Studies. “I think it speaks to the lack of law enforcemen­t monitoring what’s happening in the pharmacies.”

Finding tainted pills in a Mexican pharmacy doesn’t take much doing: Pay a visit to a certain sparse shopping plaza near Tijuana’s red light district. Stroll past the picturesqu­e stores and yacht-lined docks of Cabo San Lucas. Amble through a shopping district bustling with wealthy tourists in San José del Cabo.

In tourist districts in these three cities, there are signs for farmacias seemingly every few steps. It’s not rare to see two or three on a block. The shops’ windows and whitewashe­d walls are often plastered with block lettering advertisin­g a cornucopia of pharmaceut­icals. Some have sandwich boards on the sidewalk advertisin­g pills.

Most of them display the brightgree­n cross familiar to anyone who’s tried to get a prescripti­on filled in Europe. Much of this slapdash street advertisin­g isn’t for the big chain pharmacies, but for the smaller ones — the independen­t and mom-and-pop shops.

One farmacia in San José del Cabo offered mini Buddha statues, incense burners and other tchotchkes alongside brightly lighted display cases of pill bottles neatly arranged on gleaming mirrored shelves. In Cabo San Lucas, one shop near a large dockside shopping mall featured a few racks of toys inches away from stacked boxes of medication. But in many stores, most of the tile floor space sits empty; there’s little pretense of selling other wares.

Twice in January, two Times reporters traveled to Mexico with testing strips to check more than a dozen pills for dangerous adulterant­s.

In farmacia after farmacia in Tijuana, Cabo San Lucas and San José del Cabo, they asked for Percocet and oxy and Adderall. They asked how strong the pills were. They said they planned to split the pills or use them to study or party or in some cases didn’t give a reason why they wanted the powerful drugs. None of the pharmacist­s inquired further.

Invariably, the tablets were kept in some hidden spot. Though bottles of less tightly controlled medication­s like Xanax or Viagra or Ultram were often on display in glass cases, more powerful and more closely regulated substances like oxycodone — whether real or fake — were secreted away.

The tablets cost $15 to $35 each, depending on the shop and the alleged potency. It’s a price point high enough to be out of range for many local drug users but within the reach of many tourists. Pharmacies such as these accept payment in most any format — credit card, pesos or dollars.

At one store in Tijuana, all the drugs turned out to be legitimate — or at least they did not contain fentanyl. At another, a $25 blue pill labeled M30 and sold as “Mexican oxycodone” tested positive for fentanyl, while a $25 blue pill labeled K9 and sold as “American oxycodone” did not. A single 30-mg Adderall — for $25 — came up positive for methamphet­amine.

In Cabo San Lucas, where permissive pharmacies catering to tourists seemed even easier to find, nine samples from four drugstores tested positive for adulterant­s: Six came up for fentanyl, and three for methamphet­amine.

Twenty miles away in the resort town of San José del Cabo, a blue oxycodone pill from one store tested positive for fentanyl, while a white one from another did not. Among the three cities, several stores declined to sell the pills individual­ly, and two refused to sell them without a prescripti­on.

The results parallel what the UCLA-led team found in four unnamed cities in northern Mexico. Though roughly a third of the 40 pharmacies targeted in the study would not sell high-powered prescripti­on drugs over the counter, the majority did.

And of the 45 pills tested with an infrared spectromet­er, researcher­s found that 20 were counterfei­t, including 82% of the Adderall samples and 30% of the oxycodone samples. With their more precise equipment, the researcher­s were able to get more granular results — and to determine that three of the oxycodone samples were positive for heroin.

They, like The Times, also found that all of the counterfei­t pills came from stores in areas frequented by tourists, in locations that often featured English-language medication advertisem­ents.

But the team’s work is a preliminar­y study — a pre-print that has not been peer-reviewed — and Shover said there are several important unknowns.

“We don’t know exactly when this started, and we don’t know how widespread it is,” she said. “We don’t know who’s buying these pills, we don’t know who’s taking them, and we don’t know what’s happening to the people who take them. The most important unknown is probably how many people have died or had serious health consequenc­es from it, and we don’t have any idea.”

Mexican death data are notoriousl­y imprecise. Experts who study drug deaths say that’s partly the result of a long wave of drug-related killings that have overwhelme­d the country’s forensic services and made thorough testing nearly impossible.

When somebody dies in Mexico, a physician can note the suspected cause on a death certificat­e, but that’s only if there’s a physician involved, said Dr. David Goodman Meza, an assistant professor at the David Geffen School of Medicine at UCLA and one of the study’s coauthors.

If there’s no death certificat­e, then the country’s forensic medical service, known as SEMEFO, handles the investigat­ion.

“However, SEMEFO is super back logged,” Goodman-Meza said. “The homicide numbers are incredibly high, so those likely get priority. And that means they’re not digging deep on other deaths or doing advanced toxicology to know if drugs were involved.”

Instead, overdose deaths are chalked up to broader, catchall causes.

“The default when you don’t have an explanatio­n is to say that the person died of a cardiopulm­onary arrest,” he continued. “But, I mean, we all die because our hearts stop.”

In 2020, the Mexican government attributed just 19 deaths to opioid use. The U.S. State Department, meanwhile, noted two drug-related deaths of Americans in Mexico that year.

Those figures are “probably very low,” said Romain Le Cour Grandmaiso­n, senior expert with the Global Initiative Against Transnatio­nal Organized Crime. “I would imagine it’s a lot more, but it’s impossible to say how many.”

It’s also often impossible to know where a specific laced pill came from, but, according to a bipartisan congressio­nal report issued last year, Mexican drug cartels are the ultimate source for many of them.

Cartels first bet big on fentanyl in the 2010s, importing the drug straight from China to mix into the powdered heroin most prevalent in East Coast drug circles. As recently as four years ago, Chinesemad­e fentanyl still dominated America’s illicit supply, according to the congressio­nal report.

But cartels knew they could make more money by producing it themselves. So they began importing precursor chemicals, setting up clandestin­e labs and flooding the market with Mexican-made fentanyl, according to Fernando Montero Castrillo, who researches opioid markets at Columbia University’s HIV Center for Clinical and Behavioral Studies.

In the years that followed, the amount of fentanyl seized by U.S. Customs and Border Protection more than tripled, from 4,800 pounds in 2020 to 14,700 pounds last year.

“Pretty much all the fentanyl that comes into the United States comes from Mexico now,” Castrillo said. “Very little comes in from China.”

Though federal and local authoritie­s in Mexico did not respond to requests for comment, the Mexican government has previously said it is working to stem the f low of chemicals used to produce fentanyl.

Cartels are almost certainly the source of the counterfei­t pills appearing in drugstores, said Farfán Mendez.

But pharmacy owners are most likely not buying directly from the criminal organizati­ons. There are typically networks of middlemen, she said, so it’s unclear how many pharmacist­s even know they are selling laced pills.

When reporters visited last month, at least a few drugstore workers seemed aware their overthe-counter offerings were unusually potent.

“This one’s very strong,” cautioned a man working one afternoon behind the counter at a pharmacy less than half a mile from the U.S.-Mexico border in Tijuana. He was differenti­ating between two pills he presented when asked for oxycodone: the one he pointed out, which later tested positive for fentanyl, and one that came up negative.

The fact that reporters and researcher­s were so easily able to find drugstores selling fentanyl-laced tablets in multiple Mexican cities “signals that [customers] go into these pharmacies looking for counterfei­t oxys,” said Farfán-Mendez. “So I can see the incentive to supply it.”

But cartels could be moved to reconsider that approach “if we start seeing a number of deaths in a certain area, especially if they are American tourists” and police crack down on the practice.

Given the shortcomin­gs in Mexican death data, spotting those deaths could be difficult — which means cartels will have little reason to curb their pill trade.

“If it’s profitable and there’s not a lot of enforcemen­t,” she said, “they’re going to keep doing it.”

 ?? Photograph­s by Wally Skalij Los Angeles Times ?? IN TOURIST DISTRICTS in Cabo San Lucas, Mexico, pharmacies catering to Americans seem to be everywhere. Some drugstores there and in other northweste­rn Mexican cities are selling tainted pills.
Photograph­s by Wally Skalij Los Angeles Times IN TOURIST DISTRICTS in Cabo San Lucas, Mexico, pharmacies catering to Americans seem to be everywhere. Some drugstores there and in other northweste­rn Mexican cities are selling tainted pills.
 ?? ?? EXPERTS generally believed pills sold in Mexican pharmacies were what store owners said they were. That’s no longer always true.
EXPERTS generally believed pills sold in Mexican pharmacies were what store owners said they were. That’s no longer always true.
 ?? Photograph­s by Wally Skalij Los Angeles Times ?? THE TIMES found that 71% of the 17 pills tested came up positive for more powerful drugs. Above, a street in Cabo San Lucas.
Photograph­s by Wally Skalij Los Angeles Times THE TIMES found that 71% of the 17 pills tested came up positive for more powerful drugs. Above, a street in Cabo San Lucas.
 ?? ?? A STATE SENATOR says of The Times’ findings: “Americans travel to these locations, and they are at risk in a way that wasn’t apparent before.” Above, the resort city of Cabo San Lucas.
A STATE SENATOR says of The Times’ findings: “Americans travel to these locations, and they are at risk in a way that wasn’t apparent before.” Above, the resort city of Cabo San Lucas.
 ?? ?? IN CABO San Lucas, testing on an Adderall pill came up positive for meth. Nine samples from four drugstores were tainted.
IN CABO San Lucas, testing on an Adderall pill came up positive for meth. Nine samples from four drugstores were tainted.

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