Miami Herald

DeSantis says newest booster increases chances of COVID infection. PolitiFact says: Not true

- BY YACOB REYES PolitiFact

“Almost every study now has said with these new boosters, you’re more likely to get infected with the bivalent booster.”

Florida Republican Gov. Ron DeSantis, on Jan. 17, during a press conference

As he proposed to extend the state’s ban on mandates for COVID vaccines and face masks, DeSantis lobbed a flurry of criticism at President Joe Biden and “the medical establishm­ent.”

“They were not following the science,” DeSantis said at the news conference in Panama City Beach. “Almost every study now has said with these new boosters, you’re more likely to get infected with the bivalent booster.”

Fewer than 11% of eligible Floridians have received an updated booster vaccine, according to the Centers for Disease

Control and Prevention.

The bivalent booster, which contains components of the original COVID virus and the omicron variant, is designed to provide broad protection against illness or hospitaliz­ation from those COVID strains.

Research into the efficacy of the bivalent booster in preventing infection continues.

Broadly speaking, COVID vaccines do not prevent infection; they prevent the virus from spreading within the body and causing severe illness, according to Johns Hopkins

University. Early CDC research shows that people who got the booster were 84% less likely to be hospitaliz­ed from COVID.

The data collected on the booster’s ability to curb infection is early and limited. Some clinical trials have shown that bivalent shots are no more equipped to prevent people from contractin­g COVID than the original vaccines.

Although some people have suggested the bivalent booster offers little protection against infection, DeSantis went further. He said people who received the bivalent booster shot were more susceptibl­e to COVID than those who hadn’t.

The governor’s press office responded to PolitiFact’s inquiry about the claim, citing two articles and three studies, two of which are not yet peerreview­ed. The most recent came from the Cleveland Clinic and was discussed in an opinion article in The Wall Street Journal.

Dr. Nabin Shrestha, an infectious-disease physician and one of the study’s authors, told PolitiFact the data did not find a link between the bivalent shot and a higher risk of contractin­g COVID. The early conclusion was the opposite of what DeSantis said: The dose is, in fact, effective in preventing infection.

Cleveland Clinic researcher­s examined the bivalent booster’s effectiven­ess in preventing infection among 51,011 healthcare workers — some of whom had not received the booster — from September to

December 2022. Pfizer and Moderna offer the bivalent booster, which the FDA authorized in August.

Over those four months, about 5% of the clinic’s employees contracted COVID. The researcher­s then estimated that the bivalent booster was about 30% effective in reducing the likelihood of contractin­g the virus.

The Cleveland Clinic researcher­s were not trying to determine the bivalent vaccine’s effectiven­ess in preventing severe illness or hospitaliz­ation.

“The study wasn’t measuring the vaccine causing infection,” said Jill Roberts, a public health professor at the University of South Florida. “The study was measuring the efficacy of the bivalent vaccine in preventing infection.”

What drove coverage in outlets like The Wall Street Journal was an “unexpected” associatio­n researcher­s found between the number of prior vaccine doses and an increased risk of contractin­g

COVID. People with three or more doses of the vaccine had a higher chance of getting infected.

That finding quickly overshadow­ed the protection the bivalent shot provided. The Wall Street Journal opinion piece cited the Cleveland Clinic’s study as evidence that vaccine boosters are making “the population as a whole” more vulnerable to COVID.

Andrea Pacetti, the Cleveland Clinic’s public and media relations director, told PolitiFact that the study population, whose average age was 42, is not reflective of the general public.

“The study was done in a younger, relatively healthy, healthcare employee population. It included no children, very few elderly individual­s and likely few immunocomp­romised individual­s,” Pacetti said. “Therefore, we urge caution in generalizi­ng the findings to the public, which can include different population­s.”

More than 50% of the healthcare workers participat­ing in the clinic’s study had received three or more doses of a COVID vaccine; only 12% were not vaccinated.

Dr. René Najera, an epidemiolo­gist and director of the Center for Public Health at the College of Physicians of Philadelph­ia, said the Cleveland Clinic study’s outcome was unsurprisi­ng given the characteri­stics of the research subjects — mostly vaccinated healthcare workers.

If the majority of the study population received three or more doses of a COVID vaccine, for instance, then it is reasonable to assume that the majority of COVID cases would occur in that population.

“Those who were studied were healthcare workers: more likely to be exposed, more likely to be vaccinated as well,” Najera told PolitiFact. “If the study is found to be sound through peer review, its findings would only be applicable to healthcare workers in large settings such as the Cleveland Clinic, not the general public.”

Pacetti further emphasized that the study has not yet been peer reviewed, and “more research is needed to either confirm or refute this finding.”

The Cleveland Clinic acknowledg­ed that two other studies had found a similar associatio­n between the number of prior vaccine doses and an increased risk of contractin­g COVID, though it had similar limitation­s. One of the studies had not yet been peer reviewed, and the other examined only healthcare employees. And even with that finding, the Cleveland Clinic’s study did not suggest the bivalent booster increased the likelihood of infection.

DeSantis’ “statement is incorrect,” Najera said. “That conclusion cannot be drawn from that study, and the authors state that it is not designed to evaluate that associatio­n.”

POLITIFACT’S FINDING: DESANTIS’ CLAIM FALSE

DeSantis said, “Almost every study now has said with these new boosters, you’re more likely to get infected with the bivalent booster.”

An unpublishe­d study from the Cleveland Clinic examined the bivalent COVID booster’s effectiven­ess in preventing infection among a group of about 50,000 healthcare workers.

However, one of the study’s authors told PolitiFact that the research did not find an associatio­n with the bivalent booster and a higher risk of COVID. The study found that the bivalent booster is 30% effective in preventing infection from the virus.

The researcher­s did find that there could be an associatio­n between the number of prior vaccine doses and an increased risk of contractin­g COVID. Still, that finding did not suggest the bivalent booster could cause infection or increase the likelihood of infection.

 ?? ?? Florida Gov. Ron DeSantis said at a press conference Jan. 17 that if people were vaccinated with the new bivalent booster, they were ‘more likely’ to get infected with COVID.
Florida Gov. Ron DeSantis said at a press conference Jan. 17 that if people were vaccinated with the new bivalent booster, they were ‘more likely’ to get infected with COVID.

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