Milwaukee Journal Sentinel

Scientists edit gene to create low-fat pigs, study says

- Najja Parker

Want to enjoy bacon without the guilt? Scientists are using a gene-editing tool to create low-fat pigs, so you can.

Chinese researcher­s recently conducted an experiment, published in the Proceeding­s of the National Academy of Scientists, to determine how geneticall­y modified pigs can “improve pig welfare and reduce economic losses,” the study said.

To do so, they used a tool called CRISPR to produce a gene that helps pigs burn fat to stay warm. While other mammals, such as mice and rats, already have this gene, pigs do not.

Scientists injected a mouse version of the gene into embryonic pig cells, which were then coaxed to make more than 2,000 pig embryo clones that were geneticall­y identical.

Twelve male piglets with the new gene were born from the embryos, and those newborns had 24% less body fat than pigs without the gene.

The low-fat pigs “showed an improved ability to maintain body temperatur­e during acute cold exposure, but they did not have alteration­s in physical activity levels or total daily energy expenditur­e,” the authors wrote. They also said the gene “dramatical­ly decreased fat deposition.”

It’s unclear whether the change affects the taste and quality of the pork produced.

Furthermor­e, the safety of the CRISPR gene hasn’t been completely proven, but scientists are still hopeful.

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