Milwaukee Journal Sentinel
3 win Nobel Prize for showing how cells sense low oxygen
NEW YORK – Two Americans and a British scientist won a Nobel Prize on Monday for discovering details of how the body’s cells sense and react to low oxygen levels, providing a foothold for developing new treatments for anemia, cancer and other diseases.
Drs. William G. Kaelin Jr. of Harvard University, Gregg L. Semenza of Johns Hopkins University and Peter J. Ratcliffe at the Francis Crick Institute in Britain and Oxford University won the prize for advances in physiology or medicine.
The scientists, who worked largely independently, will share the $918,000 cash award, said the Karolinska Institute in Stockholm.
The Nobel committee said scientists are focused on developing drugs that can treat diseases by either activating or suppressing the oxygen-sensing machinery. Such manipulation could help in attacking cancer cells, experts said.