Milwaukee Journal Sentinel

Vaccine appears to protect against monkeypox, CDC says of results

- Amanda Seitz

WASHINGTON – At-risk people who received a single dose of the monkeypox vaccine in U.S. efforts against the virus appeared to be significantly less likely to get sick, public health officials announced Wednesday, even as they urged a second dose for full protection.

It was the first look public health officials have offered into how the Jynneos vaccine is affecting monkeypox, a virus that is primarily spread among men who have sex with infected men.

“These new data provide us with a level of cautious optimism that the vaccine is working as intended,” Rochelle Walensky, director of the Centers for Disease Control and Prevention, said Wednesday.

Roughly 800,000 first and second doses of the vaccine have been administer­ed across the country to people who are considered high risk for becoming infected with the virus, White House National Monkeypox Response Coordinato­r Bob Fenton said.

There is no scientifically conclusive data available to prove effectiveness of the Jynneos vaccine against monkeypox.

But the CDC’s new real-world figures show that unvaccinat­ed men between the ages 18 and 49 who were considered eligible for the vaccine were 14 times as likely to become infected with monkeypox as those who had one dose at least two weeks earlier. The data came from 32 states for cases between July 31 through Sept. 3.

Still, Walensky said, lab studies show the highest level of immunity from the virus is reached after people get a second dose of the vaccine, calling it “really important.”

The U.S. leads the world in monkeypox cases. So far more than 25,000 infections of the virus, which can cause rash, fever, body aches and chills, have been reported.

The country suffered from early problems in its response, with U.S. officials struggling to distribute the vaccine after the first case was detected in May. As some cities and counties tried to stretch the limited supply this summer, they stopped offering the recommende­d second dose of the shot.

“We’re really asking providers to do outreach to get people their second doses,” Walensky said.

Public health officials also announced changes Wednesday to who is eligible for the vaccine and how they can get it.

The new CDC guidance is intended to reach more people who might be at risk for monkeypox exposure.

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