Oh, brother!

ONE hunk or two? Or even three? Great genes run in the families of these smokin’-hot bros! These Hollywood hunks grew up together and turned out to have what it takes — from smoldering looks to soaring careers.

CASEY & BEN AFFLECK

Oscar-winning sibs Ben and Casey Affleck both started as child performers and became star actors and directors! Ben, 48, has had his share of clunkers — “Gigli,” anyone? — but always comes out on top, from “Gone Girl” to “Argo.” Baby bro Casey, 45, is not far behind, with the “Ocean’s” series of heist movies.

MARLON, KEENEN IVORY & SHAWN WAYANS

You’d be hard-pressed to find a family as funny, entrepreneurial and good-looking as the Wayans brothers! Marlon, 48, Shawn, 50, and Keenen Ivory, 62, forever changed the landscape of comedy with their irreverent sketch show “In Living Color,” which ran from 1990 to 1994, and the “Scary Movie” franchise.

DOUG & BRAD PITT

Star-gazers couldn’t stop talking about Brad, 57, ever since his debut as Geena Davis’ eye-candy in 1991’s “Thelma & Louise.” The star still commands center stage, from his Oscar last year to his ongoing

“Fight Club” divorce with Angelina Jolie. Brother Doug,

54, is famous in an entirely different sphere — philanthropy!

JAMES & DAVE FRANCO

Multi-talented James, 42, often goes way out there in his roles — like playing a hiker who cuts off his arm to escape in “127 Hours.” Younger bro Dave, 35, is making a “Superbad” career for himself, too — his roles on “Scrubs” and the film “21 Jump Street” jumpstarted him to fame.