National Enquirer

MIX ’N’ MATCH MEDS CRUSH ALZHEIMER’S!

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AHIGHLY effective treatment to knock out

Alzheimer’s disease — consisting of two existing drugs — may have been hiding in plain sight for more than half a century, experts said. Groundbrea­king research from Chicago’s Rush University Medical Center found a cocktail of gemfibrozi­l and retinoic acid, which have been on the market for decades, reversed brain damage caused by the disease in animal studies by counteract­ing Alzheimer’scausing brain plaques! Gemfibrozi­l is an old-school cholestero­l med first patented in 1968 but largely replaced by statins, and retinoic acid, a vitamin A derivative, is used to treat everything from acne to cancer.

According to researcher­s, the drug combo displayed the uncanny ability to zero in on cells called astrocytes, which enable the accumulati­on of amyloid beta — the gooey plaques that destroy brain function and are hallmarks of Alzheimer’s.

But gemfibrozi­l-retinoic acid dosing forced the astrocytes to reverse their destructiv­e process, reduce the plaques and improve cognitive function — in effect, acting as brain “clearing machines,” the scientists said.

Shockingly, someone is diagnosed with Alzheimer’s every 65 seconds in the U.S. More than 6 million people live with the disease — including legendary crooner Tony Bennett, 95 — but that figure is expected to more than double in the next 30 years!

However, study author Dr. Sumita Raha said her team’s lab results suggest low-dose gemfibrozi­l and retinoic acid “might be repurposed as a treatment for reducing the plaque burden and improving cognition.”

It’s not yet known when the experiment­s might advance to a human clinical trial, but research into the potential treatment continues.

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