New Haven Register (New Haven, CT)

U.S. vaccines surge while rest of world waits

- By Gregg Gonsalves Gregg Gonsalves is an assistant professor of epidemiolo­gy (microbial diseases) at the Yale School of Public Health, associate (adjunct) professor of law at Yale Law School, and co-director of the Global Health Justice Partnershi­p at Ya

I am sorry to tell you that you’re not getting a COVID-19 vaccine appointmen­t for a while. Actually, you’re not getting a vaccine until 2022 or perhaps 2023. We only have a few doses for Connecticu­t, fewer for New Haven, and can only provide a COVID-19 vaccine to 25 percent of Americans this year if we’re lucky. Sorry. Better luck next pandemic.

Sounds like a joke, right? You know there is plenty of vaccine out there, so this must just be a terrible attempt at humor.

Right?

For many low- and middleinco­me countries, this is no joke. In fact, the United Nations-led COVAX facility, a global initiative aimed at equitable access to COVID-19 vaccines, has said that it can only provide 27 percent coverage for low-income countries this year. How did this happen? Well, first many rich countries bought up vaccine supplies with pre-orders of vaccines in developmen­t earlier in 2020, with some countries able to cover their entire population­s several times over while poor nations could not even secure a single dose.

A broad coalition of hundreds of nongovernm­ental organizati­ons, multilater­al agencies, world leaders, researcher­s, clinicians and legal experts has been calling for a people’s vaccine for close to a year now, asking for “a global guarantee which ensures that, when a safe and effective vaccine is developed, it is produced rapidly at scale and made available for all people, in all countries, free of charge.” However, rich countries, powerful figures like Bill Gates and, most importantl­y, the pharmaceut­ical industry itself have other ideas. In fact, it’s an old idea: the market will provide. Companies will eventually get around to making enough vaccine for everyone, they’ll get around to making agreements, one by one, with local manufactur­ers and contract for additional production in middle-income countries like India and South Africa. Until then, you’ll have to wait.

This is déjà vu all over again. I was around for the battles to get AIDS drugs to the Global South. Who said it couldn’t be done back in the late 1990s, early 2000s? Bill Gates. The pharmaceut­ical industry. Rich countries around the world. But it got done because some lowand middle-income countries, like Brazil and Thailand, didn’t take no for an answer and started making their own antiretrov­iral medicines. In the meantime, a coalition of advocates, clinicians and scientists rose up to challenge the orthodoxy of global health and developmen­t — one that said it was better to have Africans wait for an AIDS vaccine, or cast aspersions on the residents of an entire continent in suggesting “Africans couldn’t tell time,” and couldn’t possibly adhere to taking their AIDS medication­s like the rest of us.

Then, as now, the call from many of us has been to use the production capacity of the rest of the world to ensure access to these critical medical interventi­ons for everyone. For AIDS drugs, the production was a simpler task, and many companies ended up making generic equivalent­s of key antiretrov­irals once the resistance of the big men and women of global health was overcome. For COVID-19 vaccines, which are more difficult to make, the task is more complicate­d, and production on the scale needed to cover everyone will require tech transfer from the companies; the subsidizat­ion of the constructi­on of new facilities to make the vaccines, their precursor molecules and other commoditie­s necessary for manufactur­e; as well as the sharing of resources, expertise and intellectu­al property.

This last item sends Bill

Gates, the pharmaceut­ical industry and many rich-country government­s into a frenzy. They claim that relaxing IP protection­s in a global health emergency isn’t the answer. The director general of the World Health Organizati­on disagrees, as do many other experts.

But this is about control and who is in charge. With relaxation of intellectu­al property restrictio­ns across the board on COVID-19, instead of the oneby-one voluntary licenses being struck between originator companies and others around the world, we could plan and work together without this hurdle. Companies would be paid to participat­e in a collective effort, a Marshall Plan for vaccines, even though American taxpayers invested billions in the vaccines in 2020. Without a coordinate­d, global strategy to publicly scale up vaccines now, we will simply be held hostage to the market, its motives and its timeline, and then have to wait for years in line for a vaccine, depending on where we live on this planet.

 ?? Erik Trautmann / Hearst Connecticu­t Media ?? A nurse draws up a vaccine for volunteers at a clinic in Norwalk recently.
Erik Trautmann / Hearst Connecticu­t Media A nurse draws up a vaccine for volunteers at a clinic in Norwalk recently.

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