Advancements in medicine

The Cleveland Clinic’s list of the top 10 medical breakthroughs of 2022 is out and it highlights the following:.

1. Next Generation mRNA Vaccines: The development of new ways to create, purify and deliver RNA mean mRNA vaccines might be used to eliminate many challenging diseases.

2.PSMA-TargetedTherapy: Prostate-specific membrane antigen positron emission tomography (PMSA PET) is a new imaging technology. It can be used in conjunction with CT or MRI scans to provide early and accurate info on where prostate cancer cells are hiding.

3. New Treatment for the Reduction of LDL: A twice-ayear injection with Inclisiran is used with statins to achieve reduction of LDL-C.

4. A Novel Drug for Treatment of Type-2 Diabetes: The once-a-week injectable of glucose-dependent insulinotropic polypeptide (dual GIP) and glucagon-like peptide receptor agonist (GLP-1) stimulates release of insulin and blocks the hormone glucagon, reducing glucose spikes after eating and slowing digestion.

5. Breakthrough Treatment for Postpartum Depression: A neurosteroid infusion is delivered intravenously for 60 hours straight, reducing the body’s stress response.

6.-10. These next are just as impressive: No. 6 Targeted Medication for Hypertrophic Cardiomyopathy. No. 7 NonHormonal Alternatives for Menopause. No. 8 Implantable for Severe Paralysis. No. 9 Artificial Intelligence for Early Detection of Sepsis. No. 10 Predictive Analytics and Preventing High Blood Pressure.

My additional top breakthroughs: A water pill and an erectile dysfunction pill to reduce the risk of Alzheimer’s — both are in controlled trials.

Health pioneer Michael Roizen, M.D., is chief wellness officer emeritus at the Cleveland Clinic and author of four No. 1 New York Times bestsellers. His next book is “The Great Age Reboot: Cracking the Longevity Code for a Younger Tomorrow.” Do you have a topic Dr. Mike should cover in a future column? If so, please email questions@ GreatAgeReboot.com.