New York Post

Get your giggle back

FDA-approved magnets may treat depression better than meds alone

- By MOLLY SHEA

IN August, Michele Pagano laughed for the first time in months.

“I was watching a movie, and I just blurted out a laugh,” she says. That small chuckle was a big deal for Pagano, a 35-year-old property manager who lives in Greenwich, Conn., who couldn’t remember the last time she’d felt happy.

“I covered my mouth and started crying because I was so overwhelme­d that I actually had that emotion again,” says Pagano, who has suffered from clinical depression for the past 20 years. For her, it was a sign that transcrani­al magnetic stimulatio­n, or TMS — a little-known psychiatri­c treatment she’d turned to after exhausting every other option — was working.

TMS — which was approved by the Food and Drug Administra­tion in 2008 and has been gaining popularity since — works by stimulatin­g the part of your brain that controls joy. “When that’s inactive, it causes depression,” Dr. Tarique Perera, who treats patients with TMS at his Greenwich-based office, tells The Post.

“With medication, only 30 percent of patients get better [on the first try], and about 50 to 60 percent of patients don’t get well,” Perera says. “TMS can get around 50 percent of patients well if medication has failed them, and for people who combine medication and TMS, it’s more like 75 percent.”

Patients receive the treatment via a magnetic coil placed on the head, which causes brain cells to fire in a series of pulses that lasts a half hour. For patients, it feels like small taps on the head. “The way I describe it is like a woodpecker trying to get into the side of a vinyl house,” Pagano explains. “It can be painful, and there are headaches. But I suffer from migraines, and it hasn’t worsened them.”

Patients typically require four to six weeks of five sessions per week, but Pagano has received treatment for four months and still sees improvemen­ts. Many patients will need to come back for booster sessions after a period of time. Perera says that typically occurs six months after treatment.

Insurance can cover treatment if medication hasn’t worked. Without insurance, the treatments run an average of $400 per session.

For Pagano, who’s tried myriad treatments for her long-lasting depression, TMS helps her feel like her brain cells are firing again after years of lying dormant. “The TMS is reactivati­ng my brain in the best way possible — I really feel like I’m a stronger, more confident, higher-self-esteemed woman than I was a year ago,” she says. “I have my good days and my bad days just as a ‘normal’ person would have, but I am happy to say that there are more good days than bad ones.”

Still, some worry that the treatment isn’t all it’s cracked up to be. It’s hard to test against a placebo, the traditiona­l method of testing a psychiatri­c treatment, which makes some wary. But Pagano says she’s seen enough to believe in TMS.

“I’ve been able to reprogram myself in less than six months [after] living in depression, anxiety and sadness for over 20 years,” Pagano says. “I owe [it] more than I could ever repay.”

 ??  ?? Michele Pagano has been undergoing transcrani­al magnetic stimulatio­n to treat her depression for the past four months.
Michele Pagano has been undergoing transcrani­al magnetic stimulatio­n to treat her depression for the past four months.

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