Tribe wins game, loses Miller

Francisco Lindor and Edwin Encarnacion hit sixth-inning home runs and the Indians beat the Cubs 4-1 on Wednesday night despite losing relief ace Andrew

Miller to a left hamstring injury. Miller grabbed the back of his leg after throwing two pitches to Anthony Rizzo in the seventh inning.

Lindor’s leadoff homer against Jon Lester (2-1) broke a 1-all tie in the sixth, and Encarnacion homered into the bleachers with two outs. Lester allowed only one hit until Brandon

Guyer’s two-out home run in the fifth tied it. In Los Angeles, Trevor Richards outpitched Clayton Kershaw just months removed from working as a substitute elementary school teacher, and the Marlins took advantage of a wild outing from the Dodgers’ ace to beat Los Angeles 8-6. In Cincinnati, prized prospect Ronald

Acuna Jr. singled and scored the tying run in the eighth inning of his big-league debut, and the Braves went on to beat the Reds 5-4. The 20-year-old Acuna became the youngest player in the majors when he was called up from Triple-A before the game. He went 1-for-5 and played left field.

In Baltimore, Joey Wendle had three hits and two RBIs and the Rays beat former teammate Alex Cobb and the Orioles 8-4. The game marked the return of lefty

Jonny Venters following a six-year absence and four major elbow operations, including three Tommy John surgeries.

In Toronto, Mookie Betts homered twice and drove in three runs as the Red Sox snapped their season-high three-game losing streak with a 4-3 win over the Blue Jays.

In Houston, Justin Verlander pitched seven sharp innings and the Astros beat the Angels 5-2, ending Los Angeles’ road winning streak at a team record-tying 11.

In San Francisco, Trea Turner got five hits, Matt Adams homered and drove in six runs, and the Nationals routed the Giants 15-2 to end a four-game losing streak.