New York Post

That's not all Folks!

Pig-kidney transplant a success and...

- By NATALIE O’NEILL no’neill@nypost.com

The New York City doctor behind a groundbrea­king transplant of a pig’s kidney into a human predicted on Thursday that surgeons would be able to perform the same procedure with livers, lungs and hearts in the near future — bringing hope to thousands of Americans on donor lists.

Dr. Robert Montgomery, an NYU Langone surgeon who successful­ly attached the hog organ to a brain-dead woman, said he expects live patients could begin re ce iv c li ni believes, ing the animal kidneys in cal trials in a year or two.

Within 10 years, he other previously non compatible pig parts will also be successful­ly gene-edited for the lifesaving surgery.

“I would predict we are within a year or two of a pig-to-living-human [kidney] transplant­s,” Montgomery said at a virtual press conference.

“There are a number of different groups preparing for the first clinical human trials.”

The promising gene-editing science — which involves removing a sugar that causes the human immune system to attack animal organs — could later be used on animal livers, lungs and hearts, the surgeon said.

“Ten years from now, I think we’ll be transplant­ing all of these organs from pigs,” he predicted.

Montgomery, a leader in the field of transplant­ation, also gave new details about the procedure, which could eventually help tens of thousands of people on organ-donor waiting lists in the United States.

During the innovative surgery, performed on Sept. 25, the pig kidney was attached to the blood vessels in a female patient’s thigh along with the animal’s thymus gland, which aids immune-system developmen­t to keep her body from rejecting it, Montgomery said.

The placement allowed the doctors to observe the blood-filtering organ, which remained “pink” and healthy and “with no evidence of rejection” for 54 hours, the doctor said.

“The kidney began to function, making large amounts of urine within minutes,” he said. “[It] functioned just like a human transplant.”

More data is needed to ensure that pig-kidney transplant­s would work on a widespread basis, he said.

“This is the critical intermedia­te step,” said Montgomery, who himself is a heart-transplant recipient.

“This procedure presents new hope.”

In the US, almost 107,000 people are waiting for organ transplant­s, including more than 90,000 for kidneys, whose wait times average three to five years, according to the United Network for Organ Sharing.

 ?? ?? SOW YOU SAY: NYU Langone’s Dr. Robert Montgomery (inset) says his successful­ly attaching a hog kidney to a human (illustrati­ons left) will lead to the transplant­s of other pig organs to people.
SOW YOU SAY: NYU Langone’s Dr. Robert Montgomery (inset) says his successful­ly attaching a hog kidney to a human (illustrati­ons left) will lead to the transplant­s of other pig organs to people.

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