New York Post

GOOD MORNING, CAVEMEN!

‘Early riser’ DNA

- By BROOKE KATO

The early cave dweller gets the worm.

People prone to early rising could have the Neandertha­ls to thank as a new study suggests that ancient genetic mutations could be responsibl­e for modernday sleep cycles.

A team of researcher­s from various US universiti­es found that DNA passed down from two ancestral groups of modern-day humans — Neandertha­ls and Denisovans — may have been the progenitor­s of the morning-person gene.

“This was really exciting to us, and not expected,” Tony Capra, a professor and co-director of the Biological and Medical Informatic­s program at the University of California, San Francisco, told New Scientist.

“Neandertha­ls and Denisovans passed on DNA that increased our morningnes­s, and this has been retained in modern human population­s.”

Past research has linked present-day biological benefits — fertility and immunity, for instance — to the genes of Neandertha­ls and Denisovans.

In the recent study, published Thursday in Genome Biology and Evolution, researcher­s wondered if our circadian rhythms evolved from our distant ancestors in the same way.

Researcher­s noticed the genes that became more common over time were connected to the body’s circadian clock, the 24-hour cycle that dictates the behavioral, mental and physical changes internally, The New York Times reported.

The scientists compared the genomes of three Neandertha­ls and one Denisovan to that of thousands of present-day humans, specifical­ly highlighti­ng the 246 genes responsibl­e for regulating the circadian clock. Overall, they found more than 1,000 unique genetic mutations throughout the sample groups, identifyin­g those that were specific to modern-day humans or our ancestors.

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