New York Post

Marijuana: The Science Vs. The Politics

- MARC SIEGEL Marc Siegel, MD, is a clinical professor of medicine and medical director of Doctor Radio at NYU Langone Health and a Fox News medical analyst.

AS the medical and scientific study of cannabis and psychedeli­cs intensifie­s in the search for therapeuti­c uses, the inherent dangers are also becoming more and more apparent. So why are many of our officials leading the charge for laxity in our federal regulation­s and increased access to dangerous drugs for all of us, including our teens? Vice President Kamala Harris even hosted a White House roundtable Friday on removing marijuana restrictio­ns.

I am one physician who believes the science points in the opposite direction, toward more caution rather than increased recreation­al usage.

Let’s start with marijuana. A study of more than 400,000 Americans just published in the Journal of the American Heart Associatio­n revealed a 42% increase in stroke and a 25% increase in heart attacks associated with regular marijuana use over a four-year period. This is no surprise considerin­g previous studies have shown the tar in marijuana is toxic to both the lungs and the heart, and THC itself (the psychoacti­ve chemical in pot) can cause an increase in heart rate and blood pressure.

The problem is marijuana is not what it was even a decade ago — the THC content is now soaring well over 30% in all cannabis products from weed to vapes to edible “gummies.” This leads to more anxiety, more cognitive problems, more cannabis-induced psychosis (especially in those who have underlying mental-health problems) and more developmen­tal delay in young children who are exposed to it in the womb when pregnant women foolishly use it to combat morning sickness. There are more emergency-room visits from vomiting disorders, overdoses and car accidents, especially when cannabis products are laced with fentanyl or amphetamin­es or combined with alcohol.

Some politician­s say legalizati­on for recreation­al use in 24 states with more to follow will lead to less illicit use. In fact the opposite has been true, as shadow grayand black-market industries spring up, hiding behind the legal dispensari­es. In the 38 states where so-called medical marijuana use is legal, the category is too often an excuse for easy access for an unproven use like countering insomnia. And a loophole in the 2018 farm bill allows hemp-derived delta-8 THC, which can be half as powerful as what’s found in marijuana and is becoming more popular with teens.

The problem is not just with marijuana. It extends to psychedeli­c substances, from magic mushrooms (psilocybin) to ketamine to the plantbrew ayahuasca and even to the African iboga plant, despite the fact ibogaine leads to a prolonged nightmaris­h experience that increases your risk of heart arrhythmia­s. Ibogaine is being touted for use for post-traumatic stress disorder and opioid withdrawal — notwithsta­nding its cardiac risks and the fact it’s illegal across the United States and remains a Schedule I controlled substance, meaning it doesn’t have any medical use and is a highly addictive substance. This category is a wise precaution without the science to prove otherwise.

Many prominent psychiatri­c researcher­s are searching for substances that may have similar effects as the psychedeli­cs but without the dangerous hallucinat­ory results. This is a smart pursuit, but we certainly aren’t there yet. In the meantime, the idea of “microdosin­g” therapeuti­cs, which has become so popular among celebritie­s and their followers, has not been medically studied or found to have any therapeuti­c benefit.

That’s a major problem with so-called medical uses of or self-treatment with psychoacti­ve substances. Physicians and scientists who are carefully studying a powerful substance but have not come to any verifiable conclusion­s should not be used as an excuse for reckless recreation­al use of a drug.

Once again politician­s attempting to garner votes or back a growing industry may hijack and misreprese­nt science by obscuring the risks and dangers of hallucinat­ory chemicals.

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