Northwest Arkansas Democrat-Gazette

Experts: Ricin hard to make, kills few

Poison better for small-scale attacks

- SETH BORENSTEIN

WASHINGTON — Ever since the terrorist attacks of Sept. 11, 2001, and deadly anthrax mailings that followed, the poison ricin has at times been lumped in with other bioterrori­sm agents because it comes from a relatively common plant and seems easy to make.

But the reality is that ricin has created far more scares than victims and is more a targeted poison — an assassin’s tool — than something used to attack lots of people.

Ricin is derived from the castor plant, used to make castor oil. There is no antidote and it is at its deadliest when inhaled. Ricin poisoning is not contagious.

Of all the biological and chemical terror agents, “it is one of the least significan­t; it is a poison,” said University of Maryland bioterrori­sm expert Milt Leitenberg.

Leitenberg said he was hard-pressed to remember any case when an initial chemical test that showed the presence of ricin actually turned out to be ricin. Nearly every time it is a false alarm. The Centers for Disease Control and Prevention said there’s a rapid detection test for ricin that takes 6 to 8 hours. The more complete test — the ricin toxin test — takes about 48 hours to perform and hinges on the availabili­ty of cultured cells. That second test is “considered the best test for determinin­g the presence of ricin,” the CDC said in a fact sheet on ricin.

A draft of a 2010 Homeland Security Department handbook lists only one person killed by ricin. And that was a political assassinat­ion, in 1978, of a Bulgarian dissident who was injected — via a specialize­d secret- agent style umbrella— with a ricin pellet. The CDC said others have been killed, but also by injection.

People have been poisoned with ricin after eating castor beans, but it is not as well absorbed through the digestive track as it is when it is injected or inhaled, according to the CDC.

The CDC categorize­s ricin as a “Class B” threat, which is the agency’s second-highest threat level. It ranks behind anthrax, botulism, plague, smallpox, tularemia and viral hemorrhagi­c fevers.

It can be aerosolize­d, released into the air and inhaled. The Homeland Security handbook said the amount of ricin that fits on the head of a pin is enough to kill an adult if properly prepared.

People need to put things in perspectiv­e, said Dr. Patricia Quinlisk, the medical director of the Iowa Public Health Department who has served on several federal bioterrori­sm boards. “Making ricin into something that can be released from an envelope into the air, be the right size to be inhaled and stick in the lungs is a lot to get right, especially if you are not a bioterrori­sm specialist and know how to do that. It’s not something you can do in your garage.

“It’s harder for these things to happen than most people think,” Quinlisk said Wednesday. It isn’t as easy as popular online handbooks say it is, Leitenberg said.

The list of ricin terror acts in the Homeland Security handbook includes several people who obtained or made ricin.

“Ricin is best suited for small- scale attacks rather than mass-casualty scenarios,” the Homeland Security handbook says. It says the best “route of exposure” is injection into the bloodstrea­m, as in the Bulgarian case.

The Homeland Security handbook also says inhaling ricin is more dangerous than eating it, but “formulatin­g ricin powder to produce the necessary size to be efficientl­y disseminat­ed via aerosol requires technical skill.”

Ricin powder, the handbook says, “could also be delivered to indoor targets via letters or packages.”

If a person is exposed to ricin, his clothing should be removed and he should be washed vigorously with soap and water and get medical attention, the Homeland Security handbook says.

 ??  ?? A firefighte­r from Prince George’s County, Md., in a protective suit enters a government mail screening site in Hyattsvill­e, Md., on Wednesday.
A firefighte­r from Prince George’s County, Md., in a protective suit enters a government mail screening site in Hyattsvill­e, Md., on Wednesday.

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