COLTS 34, JAGUARS 27

INDIANAPOLIS — Matt Ryan threw a 32-yard touchdown pass to Alec Pierce with 17 seconds to play, leading Indianapolis over Jacksonville.

The victory ends Indy’s two-game skid against their AFC South rival and marks the third time this season Ryan has led the Colts (3-2-1) to a comefrom-behind victory.

It’s the fifth consecutive loss in Indy for the Jaguars (2-4). The home team has won 11 in a row in this series.

Ryan followed a completely different script in this game than he had the previous five games. Instead of relying on the ground game, the Colts asked the 15-year veteran to lean heavily on short, quick throws and it worked. He finished with a franchise record 42 completions on 58 attempts with three touchdowns and 389 yards — passing Dan Marino for seventh on the NFL’s career list for yards passing.

It sure wasn’t easy — even after the Colts snapped a touchdown drought that stretched from the third quarter of Week 4 until just before halftime Sunday when Ryan found Parris Campbell on a 4-yard TD pass to cut the deficit to 14-10.

Nor after Trevor Lawrence took advantage of two defensive penalties and burned more than 10 minutes on a methodical, 18-play drive capped by a 4-yard TD pass to Christian Kirk to give the Jags a 27-26 lead. The two-point conversion pass failed.

But Ryan got one more chance — and delivered yet again by marching the Colts into field-goal position before throwing deep to Pierce on thirdand-3. Pierce wrestled the ball away from a defender near the goal line and got into the end zone to win it.