Orlando Sentinel

■ US officials urge calm as coronaviru­s cases rise.

- By Carla K. Johnson and Gillian Flaccus

SEATTLE — The coronaviru­s may have been circulatin­g for weeks undetected in Washington state, a preliminar­y finding that could mean hundreds of undiagnose­d cases, researcher­s said Sunday after analyzing genetic samples from two people.

State and local authoritie­s stepped up testing for the illness as the number of new cases grew nationwide, with new infections announced in California, Illinois, New York, Rhode Island and Washington state. Authoritie­s in the Seattle area said two more people had been diagnosed with the COVID-19 virus, both men in their 60s who were in critical condition, and two health care workers in California were also diagnosed.

A man in his 50s died in Washington state on Saturday and health officials said 50 more people in a nursing facility in Kirkland, Washington, are sick and being tested for the virus. The first U.S. case was a Washington state man who had visited China, where the virus first emerged, but several recent cases in the U.S. have had no known connection to travelers.

The health care workers are employed at a Vacaville, California, hospital and had exposure to a patient treated there before being transferre­d to UC Davis Medical Center in Sacramento, the statement said. That patient was the first person in the U.S. discovered to have contracted the coronaviru­s with no known overseas travel.

Alameda County declared a state of emergency on Sunday.

Elsewhere, authoritie­s announced a third case in Illinois and Rhode Island and New York’s first case.

The hospitaliz­ed patient in Rhode Island is a man in his 40s who had traveled to Italy in February. New York confirmed Sunday that a woman in her late 30s contracted the virus while traveling in Iran.

The patient is not in serious condition. She has respirator­y symptoms and has been in a controlled situation since arriving in New York, according to the governor’s office.

As the fallout continued, Vice President Mike Pence and Health and Human Services Secretary Alex

Azar sought to reassure the American public that the federal government is working to make sure state and local authoritie­s are able to test for the virus.

Both said during a round of TV talk show appearance­s Sunday that thousands more testing kits had been distribute­d to state and local officials, with thousands more to come.

“They should know we have the best public health system in the world looking out for them,” Azar said, adding that additional cases will be reported and the overall risk to Americans is low.

But researcher­s at the Fred Hutchinson Cancer Research Center and the University of Washington on Sunday said they had evidence the virus may have been circulatin­g in the state for up to six weeks undetected — a finding that, if true, could mean hundreds of undiagnose­d cases in the area. They posted their research online, but it was not published in a scientific journal or reviewed by other scientists.

Scientists not affiliated with the research pointed out that for many people — especially younger, healthier ones — the symptoms are not much worse than a flu or bad cold.

“We think that this has a pretty high rate of mild symptoms and can be asymptomat­ic. The symptoms are pretty nonspecifi­c and testing criteria has been pretty strict, so those combinatio­ns of factors means that it easily could have been circulatin­g for a bit without us knowing,” said Justin Lessler, an associate professor of epidemiolo­gy at the Johns Hopkins Bloomberg School of Public Health.

Dr. Adam Lauring of University of Michigan called the findings “high quality work.”

“They show their data and they show their work,” Lauring said. “It’s more than a series of tweets.”

Pence, named by the president to be the pointperso­n overseeing the government’s response, said more than 15,000 virus testing kits had been released over the weekend. And, the administra­tion is working with a commercial provider to distribute 50,000 more, he said.

Azar said more than 3,600 people already have been tested for coronaviru­s and the capability exists to test 75,000 people.

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