Orlando Sentinel

COVID-19 booster shots may soon be available

Most vulnerable in US will be first to receive increased protection

- By Caroline Catherman and Ryan Gillespie

The most vulnerable Americans may receive booster shots soon, after studies show they may not have had an adequate immune response to just two doses of Pfizer or Moderna vaccines.

“An additional dose could help increase protection for these individual­s,” said Centers for Disease Control and Prevention Director Dr. Rochelle Walensky in a Thursday White House briefing.

A CDC advisory committee is expected to meet today to review data and issue recommenda­tions for this group, which includes people who have received organ transplant­s and some cancer patients. The group accounts for less than 3% of adults, Walensky said.

A booster is not yet needed in the general population, said Dr. Anthony Fauci, the chief medical advisor to President Joe Biden. A double dose of Pfizer provides above 80% efficacy after six months, and Moderna provides more than 90% efficacy after six months, according to a recent summary in Nature.

“We believe sooner or later you will need a booster for durability of protection,” Fauci said. “The one thing we are doing is we’re preparing for the eventualit­y of doing that. So, if the data shows us we need to do that, we’ll be very ready to do that and do it expeditiou­sly.”

But some people aren’t waiting until boosters are approved by the U.S. Food and Drug Administra­tion. Several Florida residents already got a third booster vaccine dose by claiming it was their first.

The CDC estimates that at least 1 million people have taken a booster shot of the Pfizer or Moderna vaccine, with Florida among the states where this has happened the most, according to an internal report ABC News reviewed.

Walensky said people shouldn’t get a third dose on their own, as officials are studying if doing so is safe.

“It does undermine our ability to monitor safety,” she said.

The Florida Department of Health communicat­ions office in Tallahasse­e did not respond to multiple requests for comment on how Floridians were able to get third doses.

Thursday’s announceme­nt comes after the World Health Organizati­on asked wealthy nations such as the U.S. not to order boosters until 10% of the population of every country is vaccinated. WHO estimates that goal could be reached by the end of September.

Tom Unnasch, a University of South Florida professor, said that if vaccinatio­ns don’t reach the entire world, it is likely that

more infectious variants will form in poorly vaccinated countries and wind up in the U.S., as happened with the delta variant and several others.

Risk of variant spread from faraway places may be higher in Orlando, given the city hosts the nation’s 10th busiest airport. Over 21 million people came through the airport in 2020.

But Unnasch said that low vaccinatio­n rates in some countries cannot simply be solved with more vaccines. He came to this conclusion after his involvemen­t in drug distributi­on programs in remote areas of Africa.

“Just providing the vaccines to a country that doesn’t have the infrastruc­ture that’s capable of delivering those vaccines to the population is worthless,” he said. “The vaccines will come in and they’ll sit in a warehouse and expire.”

The argument could be made, he said, that the vaccines will be more effectivel­y used in the U.S. as booster shots. But ultimately, focus should be on ensuring that everyone gets the maximum amount of protection possible to avoid variants.

“None of us are protected until all of us are protected,” he said.

 ?? WILLIE J. ALLEN JR./ORLANDO SENTINEL ?? Sanford resident Dorothy Allen receives her Pfizer vaccine Thursday through the Seminole County mobile vaccinatio­n clinic inside the Seminole High School gym in Sanford. “It was easy, I didn’t have to make an appointmen­t,” said Allen. The clinics will be open from 4-7 p.m. at different schools throughout Seminole County.
WILLIE J. ALLEN JR./ORLANDO SENTINEL Sanford resident Dorothy Allen receives her Pfizer vaccine Thursday through the Seminole County mobile vaccinatio­n clinic inside the Seminole High School gym in Sanford. “It was easy, I didn’t have to make an appointmen­t,” said Allen. The clinics will be open from 4-7 p.m. at different schools throughout Seminole County.

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