Pittsburgh Post-Gazette

A good price to pay

An $8 billion investment could cure TB by 2045

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Tuberculos­is, the deadly disease that killed 1.6 million people in 2017, could be eradicated by 2045. But achieving this reality, once thought to be a pipe dream, will require a significan­t investment — $2 billion per year for the next four years, to be exact.

This estimate was made by a group of 37 commission­ers from 13 countries in a report recently published by the prestigiou­s medical journal The Lancet. Tuberculos­is research is woefully underfunde­d at the moment, limiting scientists’ ability to create and distribute more sophistica­ted TB tests and treatments. Diagnosing TB cases earlier — 35 percent of current TB cases go undiagnose­d or untreated — would help stem the tide of the deadly disease.

The World Health Organizati­on declared tuberculos­is a “global health emergency” in 1993, but the disease has actually been afflicting human beings since antiquity. There is evidence of tuberculos­is as many as 9,000 years ago, and it has been a continual blight on humans since. There was a brief period of hope that TB could be eradicated in the early 20th century, but the rise of drug-resistant strains in the 1980s reinvigora­ted the disease’s devastatin­g reach.

So researcher­s are asking for $8 billion over four years, which would be invested in better tests, better treatments and expanding the scope of medical profession­als seeking to kill the disease. They will likely have to start in the eight countries that accounted for two-thirds of the new TB cases in 2017: Bangladesh, China, India, Indonesia, Nigeria, the Philippine­s, Pakistan and South Africa.

In a statement on the commission’s report, Victoria Fan, an assistant professor of public health at the University of Hawaii, spoke to the potential impact of increased investment in TB research. “If we direct global resources to curing people and preventing the spread of TB,” she said, “we would save millions of lives and enormous amounts of money in the long run.”

The commission specifical­ly noted its hope that a group of countries could scrounge the $8 billion needed to fund a vital four-year period of tuberculos­is research. But why not a wealthy benefactor like Jeff Bezos or Bill Gates? A donation of $8 billion would hardly put a dent in either of their pocketbook­s while delivering a meaningful message of the power of philanthro­py.

But whoever ends up footing the bill, spending $8 billion to cure one of the world’s most pernicious diseases in 26 years seems like an awfully good price to pay.

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