Pittsburgh Post-Gazette

Vaccinated account for majority of COVID deaths

Expert says she is not surprised by fatality ratio shift

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For the first time, a majority of Americans dying from the coronaviru­s received at least the primary series of the vaccine.

Fifty-eight percent of coronaviru­s deaths in August were people who were vaccinated or boosted, according to an analysis conducted for The Washington Post’s Health 202 newsletter, by Cynthia Cox, vice president at the Kaiser Family Foundation.

It’s a continuati­on of a troubling trend that has emerged over the past year. As vaccinatio­n rates have increased and new variants appeared, the share of deaths of people who were vaccinated has been steadily rising. In September 2021, vaccinated people made up just 23% of coronaviru­s fatalities. In January and February this year, it was up to 42%, per our colleagues Fenit Nirappil and Dan Keating.

“We can no longer say this is a pandemic of the unvaccinat­ed,” Ms. Cox told The Washington Post.

Being unvaccinat­ed is still a major risk factor for dying from COVID-19. But efficacy wanes over time, and an analysis out last week from the Centers for Disease Control and Prevention highlights the need to get regular booster shots to keep one’s risk of death from the coronaviru­s low, especially for the elderly.

Dr. Anthony Fauci, the nation’s preeminent infectious-disease expert, used his last White House briefing Wednesday ahead of his December retirement to urge Americans to get the recently authorized omicronspe­cific boosters.

“The final message I give you from this podium is that please, for your own safety, for that of your family, get your updated COVID-19 shot as soon as you’re eligible,” he said.

White House press secretary Karine Jean- Pierre tweeted:

“Dr. Fauci is a pillar of the public health community. From HIV and AIDS to Ebola to COVID, he has kept the American public informed and prepared through multiple crises. It was an honor having him in the briefing room to remind Americans on the importance of getting vaccinated.”

Ms. Cox, like many experts, says she’s not surprised by the ratio shift. There are a few reasons:

• At this point in the pandemic, a large majority of Americans have received at least their primary series of coronaviru­s vaccines, so it makes sense that vaccinated people are making up a greater share of fatalities.

• Individual­s at greatest risk of dying from a coronaviru­s infection, such as the elderly, are also more likely to have received the shots.

• Vaccines lose potency against the virus over time and variants arise that are better able to resist the vaccines, so continued boosters are needed to continue to prevent illness and death.

• The BA.5 omicron subvariant became dominant in July and consistent­ly accounted for the majority of new coronaviru­s infections across the United States until earlier this month. The highly transmissi­ble strain fueled a surge of new infections, reinfectio­ns and hospitaliz­ations throughout the summer.

It’s still true that vaccinated groups are at a lower risk of dying from a COVID19 infection than the unvaccinat­ed when the data is adjusted for age. An analysis released by the CDC last week underscore­s the protection that additional booster shots offer against severe illness and death as immunity wanes.

Let’s take a look at deaths in August, when the highly contagious BA. 5 variant reached its peak:

• That month, unvaccinat­ed people aged 6 months and older died at about six times the rate of those who had received their primary series of shots.

• People with one booster dose were even better protected. Unvaccinat­ed people over the age of 5 had about 8 times the risk of dying from a coronaviru­s infection than those who received a booster shot.

• Among individual­s who were eligible to receive additional booster shots, the gap is even more striking. Unvaccinat­ed people 50 and up had 12 times the risk of dying from COVID-19 than adults the same age with two or more booster doses.

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