Pittsburgh Post-Gazette

RESPIRATOR­Y VIRUS PREVENTION The time is now

- By Catharine I. Paules and Emma G. Guare Catharine Paules is an infectious diseases physician at Penn State Health. Emma Guare is a student at Penn State College of Medicine.

While many look forward to gathering with friends and family, holiday season get-togethers carry a risk of respirator­yvirus infections.

Clinicians are tracking three main viruses that may make this a difficult respirator­y virus season: influenza (flu), RSV (respirator­y syncytial virus) and COVID-19. And the most surefire way to ensure you and others remain virusfreei­s to have a plan — from prevention­to treatment.

Influenza and RSV predictabl­y make an appearance during winter months each year, causing up to 600,000 and 160,000 hospitaliz­ations, and up to 50,000 and 10,000 deaths in adults, respective­ly.

COVID-19 is a newer player on the respirator­y virus stage. To date, it is responsibl­e for nearly 7 million deaths worldwide.

How COVID will fit into the annual winter surge in respirator­y illnesses is not yet clear, but cases are rising, with a 3.1% increase in hospital admissions due to COVID, per the Centers for Disease Control and Prevention, for the week beginning Dec. 3. Newer variants such as JN.1 may lead to a further surge in cases and we expect to see increased numbers of cases over the holidays, like the peak in hospitaliz­ations that occurred the week after Christmas2­022.

All three contagious respirator­y viruses can cause mild to severe illness.

This year, there’s good news. With vaccines now available for each of these viruses, we are more prepared than ever to face the threat and enjoy our holidays with peace of mind.

A recent survey from the Annenberg Public Policy Center showed that over a third of Americans are worried that the viruses will infect them or someone they love.

Factors that increase risk of severe infection include being 60 years or older, having chronic heart or lung disease, having a weakened immune system dueto illness or medication, or having other medical conditions. Even if you don’t fit into these risk groups, everyone knows someone at increased risk

― maybe among our closest friends and family ― who would be more likely to require hospitaliz­ation or even die if they caught the flu,RSV or COVID-19.

So how do we protect ourselves and our loved ones from illness this year? Front andcenter are vaccines.

Recommende­d by the CDC for more than 20 years, the influenza vaccine decreases the risk of illness by 40-60%, with an even greater reduction in severe disease. Every year, a new flu vaccine is developed to match the circulatin­g virus strains based on informatio­n from countries around the world. The CDC recommends getting the flu vaccine each fall; even if you have not gotten it yet, you still have time, as flu season is just beginning.

COVID-19 vaccines have been available since December 2020, with updates to target changes in the virus that have occurred after time. The vaccines provide short-term protection against COVID infection and, most importantl­y, provide lasting protection against severe infection leading to hospitaliz­ation and death.

If your most recent COVID vaccinatio­n was before Sept. 12, you should get an updated COVID-19 vaccine. Repeated vaccinatio­ns are needed to ensure the best protection, particular­ly if you are at higher risk for more serious infection.

Two vaccines for RSV have been approved by the Food and Drug Administra­tion for people older than 60. While these vaccines — GSK’s Arexvy and Pfizer’s Abrysvo — are relatively new, clinical trials showed that they were more than 80% effective in preventing lower respirator­y tract infection from RSV. If you are over the age of 60, you should talk with your doctor about the benefits of getting the RSV vaccine, particular­ly if you are at high risk for severe RSV.

Beyond vaccinatio­n, there is plenty you can do for added protection for yourself and those around you.

While you’re traveling and especially when in crowds, wear a mask and wash your hands frequently. If you feel under the weather or have been exposed to someone with one ofthese viruses, stay home.

Ifyou must go out, wear a mask around others to prevent spreading illness. You may also want to consider gathering outdoors or making sure indoor spaces are properly ventilated. In addition, taking a COVID-19 rapid antigen test provides anotherlay­er of protection.

If you do become infected with the flu or COVID-19, antiviral medication­s can lessen the duration and severity of symptoms. They work best when taken early; if you are sick, contact your doctor right away to see if these might help you.

Those with an increased risk of serious infection should talk with their doctor ahead of time about a “sick plan.” It should include a strategy for testing and treatment options.

The right plan will give you and your loved ones more peace of mind as the respirator­y virus season continues.

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