Pittsburgh Post-Gazette

Documentar­y features Pittsburgh work in catching medical errors

- By Anya Sostek Anya Sostek: asostek@post-gazette.com

Inside UPMC Presbyteri­an, researcher­s used genetic sequencing to identify 10 patients sick with the exact same strain of a hospital-acquired infection. They then used a machine learning algorithm to track the paths of those patients, figuring out that nearly all of them had visited the same interventi­onal radiology lab — where they found improper sterilizat­ion procedures, driven in part by a faulty training video distribute­d by the equipment manufactur­er.

Immediatel­y, they alerted the radiology lab and the manufactur­er, stopping the distributi­on of that video to improve patient safety both at Presby and beyond.

That program at Presby — and several other initiative­s nationwide — are featured in a documentar­y premiering this week at the Cleveland Internatio­nal Film Festival.

The movie, “The Pitch: Patient Safety’s Next Generation,” focuses on new technology to reduce medical errors and improve patient safety.

“It’s not easy to find technology solutions to patient safety problems,” said Mike Eisenberg, the documentar­y’s director. “They exist, they’re out there, but they aren’t in broad daylight like other technology solutions are.”

The documentar­y, funded by the Pittsburgh­based Jewish Healthcare Foundation, will also be shown in May through the JFilm Jewish film festival in Pittsburgh.

Eisenberg’s previous film, “To Err is Human,” also tackled the topic of preventabl­e medical mistakes. That film, released in 2018, received widespread acclaim but had its distributi­on curtailed by the COVID-19 pandemic. The film was inspired by the work of Eisenberg’s late father, John M. Eisenberg, director of the Agency for Healthcare Research and Quality and a pioneer in medical quality improvemen­t.

Despite leaders such as John M. Eisenberg soundingth­e alarm about medical errors since the 1990s, they are still a significan­t issue in hospital admissions. One 2023 study found that one in four patients experience­s adverse effects in a hospital, and that one in four of those is preventabl­e.

Because of his previous work in the field, The Jewish Healthcare Foundation reached out to Eisenberg about directing this documentar­y focusing on the role of technology.

And while there was no

mandate to focus on work going on in Pittsburgh, the story about the program at UPMC Presby was a natural fit.

That program, called the Enhanced Detection System for Healthcare-Associated Transmissi­on (EDS-HAT), was developed jointly with researcher­s at the University of Pittsburgh and Carnegie Mellon University.

Lee Harrison, director of the Center for Genomic Epidemiolo­gy at Pitt, and Artur Dubrawski, research professor of computer science at CMU, are both interviewe­din the documentar­y.

During its trial at UPMC between 2016 and 2018, EDSHAT was able to uncover 99 outbreaks associated with hospital-acquired infections, and was able to identify at least one transmissi­on route in 65% of those clusters. Traditiona­l methods of infection prevention over that time were only able to identify 15 of those infection cluster outbreaks.

Researcher­s estimated that the technology could have prevented 63 infectious disease transmissi­ons, had it been running in real time over that period. Since the study, UPMC has implemente­d it in their hospitals.

“It was the perfect story we wanted to tell for this film,” said Eisenberg. “Everything fell into place beautifull­y.”

The movie also features other efforts to use technology to improve patient safety, including a doctor in East Lansing, Mich., reducing the use of anesthesia by using virtual reality, a health center in Toronto using a GE command center model, and a start-up company led by a young former medical student in San Jose, Calif. trying to improvemat­ernal mortality.

“There are so many stories to tell in patient safety and they just don’t get told very often,” said Eisenberg. “In terms of what’s next, that’san untold story.”

 ?? Courtesy of The Pitch documentar­y ?? “The Pitch” focuses on new technology used to reduce medical errors and improve patient safety.
Courtesy of The Pitch documentar­y “The Pitch” focuses on new technology used to reduce medical errors and improve patient safety.
 ?? Courtesy of UPMC ?? Lee Harrison, director of the Center for Genomic Epidemiolo­gy at Pitt, is interviewe­d in the documentar­y.
Courtesy of UPMC Lee Harrison, director of the Center for Genomic Epidemiolo­gy at Pitt, is interviewe­d in the documentar­y.

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