Press-Telegram (Long Beach)

Ex-junk bond king urges medical communitie­s to speed up cures

Financier-turned-philanthro­pist Michael Milken urges applying business principles to foster quicker breakthrou­ghs

- By Mark Kreidler

Years ago, a top chemical biologist pondered ditching his cancer research to take a more lucrative commission growing healthier apples. Michael Milken stopped him.

“I told him we could probably eat the same apples for the next 20 years and be OK, but we wouldn't be OK if he didn't continue his potential groundbrea­king work,” Milken, 76, said. “Then we funded him.”

Driven by a family history of disease and his own experience with prostate cancer, Milken, the onetime junk bond wizard whose spectacula­r downfall on securities charges led to a 22-month prison term in the 1990s, has spent the past three decades trying to advance medical science so that people “can find cures to life-threatenin­g diseases within their own lifetimes.”

In “Faster Cures,” a book that is part memoir and part medical history, the financiert­urned-philanthro­pist argues for applying business principles to foster quicker medical breakthrou­ghs: more collaborat­ion and informatio­n-sharing among researcher­s, a more streamline­d path through government regulation­s, and more public and private funding to keep the best and brightest working in the field. The book was written with Geoffrey Evans Moore, a longtime associate of Milken's.

Milken, whose net worth is estimated at $6 billion, has donated $1.2 billion to medical research and public health causes and raised $1 billion for them from donors, according to a spokespers­on. Much of that is distribute­d through the Santa Monica-based Milken Institute, which funds organizati­ons around the world that support research and education.

This interview has been edited for length and clarity.

Q Was it difficult to write about your father's death from cancer and your own diagnosis of advanced prostate cancer in 1993, which was thought at the time to be terminal?

A Life-threatenin­g diseases are not separated by wealth or anything else. One in two men is going to get diagnosed with cancer in their lifetime; for women, it's 1 in 3. In the hospital room or in surgery, we're all equal. That's why I wanted to personaliz­e it because my family is no different. In the 1970s, science could not move fast enough to save my father's life.

Q Is the U.S. too slow in reaching cures?

A A train today in Europe or Asia can travel at 200 miles an hour, but the average train in the U.S. travels at the same speed as 100 years ago because you can't put faster trains on tracks that aren't more modern. Science is this train that's moving fast, but the tracks are 20th-century tracks. As science moves quickly — sequencing your genome and your microbiome, for example — many of the ways we deal with our health system still relate to what it was in the 1900s, not in this century.

Q What are those outdated practices?

A One is collaborat­ion. Thirty years ago, after

my diagnosis, I attended a prostate cancer conference at MD Anderson Cancer Center in Houston, and I noticed that no one from Memorial Sloan Kettering was presenting, and they were the other recognized top experts in the field. When I asked why, I was told by MD Anderson's people that they felt Sloan Kettering was a competitor. I said, “They're not a competitor to patients.” We've done a huge amount of work in that area to get researcher­s and scientists sharing informatio­n and working together.

QAre cancer patients getting into clinical trials at earlier stages?

AYes, but there's another element here relating to health equity. The demographi­cs of America have changed considerab­ly. Sixty years ago, 75% of everyone living in the U.S. who was not born here came from Europe. Today, more than 70% of everybody living here who wasn't born here came from Latin America or Asia, but our clinical trials are still largely Caucasian. We're not including people who will someday make up the majority of people in this country.

QYou also spend a lot of time writing about prevention, especially as it pertains to diet. Why?

AIf you went to medical school in China 30 or 40 years ago, you wouldn't have even studied diabetes because it was so rare there. Today, because of changes in the food chain and what they're eating — meatbased and fat-based diets — China has the most people with diabetes of any country in the world. That's what thousands of McDonald's and KFC and

QBut isn't the medical industry oriented toward selling treatment and not prevention?

AWhen we proposed the idea to the medical community in the '90s that you are what you eat, they said, “Prove it.” And we didn't sequence the genome until 2003, so prior to that the evidence was mostly anecdotal, but there was plenty of it.

The notion is mainstream today, but teaching doctors that nutrition makes a difference is still a minor, minor part of medical school. It should be at the forefront. We often refer to the produce section of the grocery store as the pharmacy of the 21st century.

QYour financial theories revolved around finding lower-graded bonds that produced great returns — essentiall­y, identifyin­g an undervalue­d segment of the market. Is there an undervalue­d equivalent in medicine or science?

AIt's about the democratiz­ation of capital. In medicine and science, access to financial capital serves as a multiplier effect, but the largest asset is human capital. I've spent considerab­le time trying to identify the future Ted Turners or John Malones of the world of medicine, then convincing them to go into research and funding them.

QHow do you provide financing to the most talented people in the field?

Q

Why do you fund medical research? A

My interest in medicine and science started when I was 8 years old. It accelerate­d in the '70s when my wife's mother was diagnosed with breast cancer and my father's melanoma returned. That began a search for medical solutions that I brought into my existing philanthro­py in 1982.

Who a person is and what they believe in — there has always been a lot of misinforma­tion out there, and it's only going to get worse with artificial intelligen­ce chat.

It's not just related to me. But I think the thousands of companies that we financed, and the millions of jobs created, are evidence that the ideas I put forth are today in the mainstream. All of the facts are there for one to see.

This article was produced by KFF Health News, formerly known as Kaiser Health News, a national newsroom that produces in-depth journalism about health issues and is one of the core operating programs at KFF — the independen­t source for health policy research, polling, and journalism. KFF Health News is the publisher of California Healthline, an editoriall­y independen­t service of the California Health Care Foundation.

 ?? ?? “As science moves quickly — sequencing your genome and your microbiome, for example — many of the ways we deal with our health system still relate to what it was in the 1900s, not in this century,” says Michael Milken, the former junk bond king and now philanthro­pist who's urging change in the medical community.
“As science moves quickly — sequencing your genome and your microbiome, for example — many of the ways we deal with our health system still relate to what it was in the 1900s, not in this century,” says Michael Milken, the former junk bond king and now philanthro­pist who's urging change in the medical community.
 ?? ?? Milken
Milken

Newspapers in English

Newspapers from United States