American Black Nightshade berries and leaves are traditionally eaten by Native Americans as well as modern cultures in Central American communities. Black Nightshade also has more protein, calories, fiber, calcium, iron, B vitamins, and vitamin C than spinach.
Deadly Nightshade, on the other hand, can cause delirium, hallucinations, and death when eaten in large quantities. “This is the most likely deadly doppelgänger to get you into trouble,” Lee said. “Avoiding both varieties, if you’re unsure, would be your best bet.”
Tell Them Apart: “The most obvious way to differentiate between them is that the edible Black Nightshade berries grow in bunches, as opposed to Deadly Nightshade berries which grow individually. Remember that only the ripe berries can be eaten safely, and the leaves still need to be boiled before consumption.”