San Diego Union-Tribune (Sunday)

‘FEMTECH’ MAY BE NEXT HORIZON IN HEALTH CARE

Companies creating health products for women’s needs

- BY FARAH NAYERI Nayeri writes for The New York Times.

Women represent half of the planet’s population. Yet tech companies catering to their specific health needs represent a minute share of the global technology market.

In 2019, the “femtech” industry — software and technology companies addressing women’s biological needs — generated $820.6 million in global revenue and received $592 million in venture capital investment, according to Pitchbook, a financial data and research company. That same year, the ride-sharing app Uber alone raised $8.1 billion in an initial public offering. The difference in scale is staggering, especially when women spend an estimated $500 billion a year on medical expenses, according to Pitchbook.

Tapping into that spending power, a multitude of apps and tech companies have sprung up in the last decade to address women’s needs, including tracking menstruati­on and fertility, and offering solutions for pregnancy, breastfeed­ing and menopause. Medical startups also have stepped in to prevent or manage serious conditions such as cancer.

“The market potential is huge,” said Michelle Tempest, a partner at the London-based health care consultanc­y Candesic and a psychiatri­st by training. “There’s definitely an increasing appetite for anything in the world which is technology, and a realizatio­n that female consumer power has arrived — and that it’s arrived in health care.”

She said one reason women-related needs had not been focused on in the field of technology was that life sciences research was overwhelmi­ngly “tailored to the male body.” In 1977, the U.S. Food and Drug Administra­tion excluded women of childbeari­ng age from taking part in drug trials. Since then, women have been underrepre­sented in drug trials, Tempest said, because of a belief that fluctuatio­ns caused by menstrual cycles could affect trial results and also because if a woman got pregnant after taking a trial drug, the drug could affect the fetus. As a result, she noted, “we do lag behind men.”

The term “femtech” was coined by Ida Tin, the Danish-born founder of Clue, a period and ovulation tracking app establishe­d in Germany in 2013. In an article on the company’s website, Tin recalled how she first had the idea for the app. In 2009, she found herself holding a cellphone in one hand and a small temperatur­e-taking device in the other and wishing she could merge the two to track her fertility days, rather than manually having to note her temperatur­e on a spreadshee­t.

Clue allows women to do exactly that with a few taps on their smartphone. Today, the company has a lot of competitio­n in the periodand fertility-tracking area. And plenty of other womenspeci­fic tools have come onto the market. Elvie, a London-based company, has marketed a wearable breast pump and a pelvic exercise trainer and app, both using smart technology. Another strand of femtech known as “menotech” aims to improve women’s lifestyles as they go through menopause, providing access to telemedici­ne, and informatio­n and data that women can tap into.

Finally, there are medical technology companies focused on cancer that affects women, such as cervical cancer and breast cancer.

According to the World Health Organizati­on, cervical cancer is the fourth most common cause of cancer among women around the world. In 2018, about 570,000 women had it, and as many as 311,000 died. The WHO in November announced a program to eradicate the disease completely by the year 2030.

Mobileodt, a startup based in Tel Aviv, Israel, uses smartphone­s and artificial intelligen­ce to screen for cervical cancer. A smart colposcope — a portable imaging device that is 1 1⁄2 times the size of a smartphone — is used to take a photograph of a woman’s cervix from a distance of about 3 feet. The image is then transmitte­d to the cloud via a smartphone, where artificial intelligen­ce is used to identify normal or abnormal cervical findings.

A diagnosis is delivered in about 60 seconds — compared to the weeks it takes to receive the results of a standard smear test (which, in developing countries, extends to months). In addition to this screening, doctors still use smear tests.

The technology was recently used to screen 9,000 women during a threemonth period in the Dominican Republic as part of a government-led campaign, the company announced last month. Another 50,000 women are expected be screened in the next six months.

Leon Boston, the South African-born chief executive of Mobileodt, said the privately owned company was selling into about 20 different countries including the United States, India, South Korea and Brazil, and is going into a fundraisin­g round to build on its initial seed money of $24 million.

But the leading cause of cancer among women all over the world is breast cancer. One French startup is focused on dealing with its aftermath. Lattice Medical has developed a 3D-printed hollow breast implant that allows for the regenerati­on of tissue and is absorbed by the body over time.

How it works: Post-mastectomy, the surgeon harvests a small flap of fat from the area immediatel­y around the woman’s breast and places it inside the 3Dprinted bioprosthe­sis. That piece of tissue grows inside the implant and eventually fills it out. In the meantime, the 3D-printed shell disappears completely 18 months later.

So far, tests on animals have been encouragin­g, said Julien Payen, the company’s co-founder and chief executive. Clinical trials on women are expected to start in 2022, with the aim of getting the product into the market in 2025, he added.

Asked why the global femtech market was so small for technology companies, Boston said it was partly because of the “high level of regulation” involved in medical technology.

“If your technology is incorrect and comes up with the wrong result, a woman who thinks she’s not positive for cervical cancer is actually positive,” he said. As a result, “the world of medical technology is slow to move.”

Still, prospects are favorable, according to Boston. “It’s very rare to have a totally barren market open for full potential as we have today in medical technology,” he said.

The data forecasts appear to back that up. According to a March 2020 report by Frost & Sullivan, a research and strategy consultanc­y, revenue from femtech is expected to reach $1.1 billion by 2024.

Payen explained that for the femtech market to expand and develop, there have to be many more tech companies offering genuine health benefits to women, not just well-being apps crowding the market and adding little in terms of health or medical value. He cited the example of Endodiag, a French medical technology company that allows early diagnosis of endometrio­sis and a better management of the condition.

Either way, said Payen, the industry showed promise.

“Over the last 10 years, thanks to #Metoo and other movements, women are being listened to and heard more than ever before,” Payen said. And “more and more women are running companies and investment funds,” he added.

“In 10 or 15 years from now, as a new generation takes over, things will have changed even more radically,” he said. “Femtech is clearly poised to grow.”

 ?? SUZIE HOWELL THE NEW YORK TIMES ?? “The market potential is huge” for products that address women’s health care needs, said Michelle Tempest, a partner at the London-based health care consultanc­y Candesic and a psychiatri­st by training.
SUZIE HOWELL THE NEW YORK TIMES “The market potential is huge” for products that address women’s health care needs, said Michelle Tempest, a partner at the London-based health care consultanc­y Candesic and a psychiatri­st by training.
 ?? MOBILEODT ?? Mobileodt, a startup based in Tel Aviv, uses smartphone­s and artificial intelligen­ce to screen for cervical cancer.
MOBILEODT Mobileodt, a startup based in Tel Aviv, uses smartphone­s and artificial intelligen­ce to screen for cervical cancer.

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