PATRIOTS (4-11) AT BILLS (9-6)

Today: Line: Series record: Outlook:

10 a.m. Bills by 14

Patriots lead 78-49-1. The Bills would have some margin for error concerning the postseason had they not squandered a 25-22 lead to the Patriots in October by allowing Mac Jones to cap an eight-play, 75-yard drive with a 1-yard TD pass to Mike Gesicki with 12 seconds remaining. Jones isn’t even Buffalo’s starter anymore, replaced by Bailey Zappe . ... The NFL lists 14 scenarios in which Buffalo can clinch its fifth straight playoff berth, with five based on the Bills beating New England and the remaining nine based on a tie . ... Buffalo QB Josh Allen’s 40 TDS (27 passing, 13 rushing) lead the NFL this season, and his streak of scoring in 23 straight games is the league’s longest active run.

TITANS (5-10) AT TEXANS (8-7) Today: Line: Series record: Outlook:

10 a.m. Texans by 41

Titans lead 23-20. The Texans remain in contention for both the AFC South title and a wild-card playoff spot, but a loss today would mean they’d need a lot of help next week . ... These teams played just two weeks ago in Nashville, with Case Keenum leading Houston to an improbable victory in overtime. Rookie C.J. Stroud is back today after missing that game and last week’s loss to the Browns. ... Also returning is Titans rookie QB Will Levis, who missed last week with the sprained left ankle he aggravated on the seventh and final sack in the OT loss to Houston . ... With 28 yards rushing, Titans RB Derrick Henry will become the 10th player in NFL history with five or more seasons with at least 1,000 yards rushing and 10 rushing TDS. … Titans WR Deandre Hopkins, who started his career in Houston, has caught a pass in 160 straight games to start his career.

CARDINALS (3-12) AT EAGLES (11-4) Today: Line: Series record: Outlook:

10 a.m. Eagles by 111

Cardinals lead 59-56-5. Philadelphia entered the weekend tied with San Francisco and Detroit for the best record in the NFC. The Eagles can finish anywhere from the first seed with a first-round bye to fifth in a wild-card spot . ... Eagles QB Jalen Hurts tied Randall Cunningham’s franchise record last week in accounting for 35 combined TDS . ... Cardinals QB Kyler Murray is 2-4 in six games since returning in November from an ACL tear in his right knee that sidelined him for roughly 11 months . ... Arizona coach Jonathan Gannon was the Eagles’ defensive coordinator the past two seasons, helping Philadelphia set a franchise record with an Nfl-leading 70 sacks in 2022 with the league’s second-ranked pass defense . ... Arizona’s Matt Prater is 9 of 11 on field goals of 50-plus yards, while Philadelphia’s Jake Elliott is 7 of 8.

SAINTS (7-8) AT BUCCANEERS (8-7) Today: Line: Series record: Outlook:

10 a.m. Buccaneers by 21

Saints lead 39-25. Tampa Bay can clinch the NFC South win a win today, or a tie if Atlanta loses. Bucs QB Baker Mayfield has thrown for 3,598 yards and 26 TDS vs. eight INTS. He’s completed 62 percent of his passes for 1,010 yards, with nine TDS and one INT during the four-game winning streak that’s carried Tampa Bay back to the top of the NFC South . ... Saints QB Derek Carr is one of two QBS, along with C.J. Stroud of Houston, with six 300-yard passing games in 2023. … WR Chris Olave has had 94 or more yards receiving in four of his past five games, including a seasonhigh 123 yards last week.

RAIDERS (7-8) AT COLTS (8-7) Today: Line: Series record: Outlook:

10 a.m. Colts by 31

Raiders lead 11-10. Both teams remain in playoff contention though neither can clinch a berth today . ... Raiders rookie QB Aidan O’connell played in Indianapolis a year ago when he was with Purdue in the Big Ten championship game. He had a rough game last week in the win at Kansas City, completing just nine passes for 62 yards — all in the first quarter . ... Colts RB Jonathan Taylor, the 2021 NFL rushing champ, struggled last week after missing the previous three games following surgery on his right thumb. This could be a chance to get back on track. He’s played the Raiders each of the past three years and has topped the 100-yard mark each time, running a total of 62 times for 405 yards and four scores . ... This game marks the second straight year one of these teams has had an interim coach. Indy gave Jeff Saturday his only win last season at Las Vegas. Antonio Pierce hopes to replicate that victory celebration this weekend.