San Diego Union-Tribune

SAN DIEGO BIOTECH SOLD FOR $4.8B

Bristol Myers Squibb purchases Mirati, which develops cancer drugs

- BY NATALLIE ROCHA

Mirati Therapeuti­cs, a San Diego biotechnol­ogy company developing commercial drugs for cancer treatment, was just purchased by a pharmaceut­ical giant for more than $4.8 billion.

Bristol Myers Squibb, one of the world’s largest pharmaceut­ical companies, announced Sunday evening that it will buy Mirati for $58 per share in a deal funded by cash and debt. There is potential for an additional $1 billion in milestone payments.

The deal is expected to close in the first half of next year.

“Bristol Myers Squibb’s global scale, resources and commitment to innovation will enable Mirati’s therapeuti­cs to benefit more patients, faster, and deliver on our vision

of unlocking the science behind the promise of a life beyond cancer,” said Charles Baum, founder and CEO of Mirati Therapeuti­cs, in a statement.

This acquisitio­n is part of Bristol Myers Squibb’s broader effort to expand its cancer treatment portfolio.

It picks up Mirati’s commercial non-small cell lung cancer drug Krazati, which was approved by the U.S. Food and Drug Administra­tion in December.

In the first half of this year, Krazati brought in $19.7 million in revenue, according to the company’s quarterly report. The addition of this commercial drug builds on Bristol Myers Squibb’s expansion into targeted cancer therapies beyond its current offerings of immunother­apies.

Mirati marks the second San Diego biotech snatched up by Bristol Myers Squibb recently for its oncology portfolio. Last year, it bought Turning Point Therapeuti­cs for $4.1 billion to acquire its treatments that target lung cancer and mutations that cause cancer.

Mirati Therapeuti­cs has been in San Diego developing treatments targeted at the genetic and immunologi­cal causes of cancer for 28 years. The biotech employed 593 people at the end of last year.

In addition to Krazati, Bristol Myers Squibb gains access to Mirati’s pipeline of potential treatments for lung, bile duct and skin cancer tumors, as well as tumor mutations in pancreatic, lung and colorectal cancers.

“We are excited to add these as

sets to our portfolio and to accelerate their developmen­t as we seek to deliver more treatments for cancer patients,” said Giovanni Caforio, CEO of Bristol Myers Squibb, in a statement. “With a strong strategic fit, great science and clear value creation opportunit­ies for our shareholde­rs, the Mirati transactio­n is aligned with our business developmen­t goals. Importantl­y, by leveraging

our skills and capabiliti­es, including our global commercial infrastruc­ture, we will ensure patients globally can benefit from Mirati’s portfolio of innovative medicines.”

Neither company immediatel­y responded to the Union-Tribune’s questions about how the businesses will be combined, whether Mirati’s CEO will remain on staff, and what will happen to the local workforce.

Mirati’s acquisitio­n does not come as a complete surprise. Last week, rumors were swirling after Bloomberg reported that a French pharmaceut­ical company, Sanofi, might buy Mirati.

Following the news of Bristol Myers Squibb’s purchase, Mirati’s shares closed Monday at $57.02, down $3.18 on the Nasdaq exchange.

The transactio­n will be dilutive to Bristol Myers Squibb, according to the announceme­nt.

 ?? MIRATI THERAPEUTI­CS ?? Mirati Therapeuti­cs has been developing treatments targeted at the genetic and immunologi­cal causes of cancer for 28 years.
MIRATI THERAPEUTI­CS Mirati Therapeuti­cs has been developing treatments targeted at the genetic and immunologi­cal causes of cancer for 28 years.

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