San Francisco Chronicle

Short supply:

- By Annie Vainshtein Chronicle staff writer Aidin Vaziri contribute­d to this report. Annie Vainshtein is a San Francisco Chronicle staff writer. Email: avainshtei­n@ sfchronicl­e.com

Home coronaviru­s antigen tests have become more difficult to find in Bay Area drugstores.

Rapid at-home antigen tests have become convenient tools for people hoping to quickly determine whether their cold symptoms are COVID-19.

But the tests, which are not as accurate as PCR lab tests but return results in far less time, can be hard to find in the Bay Area.

The two at-home tests approved by the Food and Drug Administra­tion are Abbott Laboratori­es’ BinaxNow and Ellume’s COVID-19 home test. But at least in the Bay Area, it’s challengin­g to find a drugstore that isn’t sold out of BinaxNow, though Ellume is far easier to get.

Calls to numerous Bay Area drug stores — including CVS and Walgreens — found that many were sold out of BinaxNow but had Ellume kits available. Store employees said that supply was variable depending on the day. Online, too, many retailers — including Walgreens and Walmart — appear to be out of stock of BinaxNow. Even if you are able to place an online order, the tests may not be shipped immediatel­y due to the high demand.

BinaxNow is cheaper than Ellume, but it’s still a significan­t cost. The product, made by Abbott Laboratori­es, comes in a two-test kit and is sold for around $23.99. Ellume has only one test swab and is sold in most places for $38.99.

“We typically don’t recommend Ellume because it’s more expensive,” said Nam Tran, a professor of pathology and laboratory medicine at UC Davis and a member of California’s COVID-19 Testing Task Force, who noted that in Davis, BinaxNow is virtually nowhere to be found.

President Biden said on Thursday that his administra­tion would use federal law to ramp up production of rapid home tests, and also ensure that retailers including Walmart, Amazon and Kroger sell test kits “at cost” starting most likely next week. “At cost” means that the seller would not make profits, but it was not immediatel­y clear what the new price would be.

BinaxNow and Ellume are the same in terms of how they collect samples, according to UCSF infectious disease expert Peter-Chin Hong.

Both are “better at detecting people with symptoms rather than people without symptoms,” he said.

Antigen tests, which detect proteins from the coronaviru­s, are less accurate than polymerase chain reaction or PCR tests, which examine small amounts of the virus’ genetic material, said Chin-Hong.

“The (antigen test) is kind of a coarse instrument,” said Chin-Hong. “It’s maybe like a child in a field looking for a helium balloon, and the balloon has to be huge and bright for the child who is the instrument, but if there are balloons that are deflated and small, the antigen won’t pick it up.”

The PCR test, by contrast, is more like a key that fits into a lock, he said.

Overall, experts say, people should use antigen tests about three to five days after exposure to the coronaviru­s, and use a PCR test — often required by schools or other workplaces — for added clarity. The two BinaxNow testing kits are meant to be used 36 hours apart, for accuracy in case a person gets a false negative. Test results are available in 15 minutes.

Ellume can take a bit longer, with some estimates of up to 45 minutes. To use it, you have to download an app and answer a number of questions.

As for the choice between BinaxNow and Ellume, Tran said, “Go with the one that is available, easy to use, and that you can afford.”

John Koval, media spokespers­on for Abbott Laboratori­es, said that the company is seeing “unpreceden­ted demand as case rates rise” and has been been scaling up manufactur­ing.

However, the company’s production was hobbled after it laid off hundreds of workers at two manufactur­ing sites and destroyed millions of test cards earlier this year, believing that demand had dwindled, according to the New York Times.

Ellume, with its app component, may not be the most intuitive test kit for the technologi­cally unsavvy — but it offers an electronic receipt for the test that can be shown to employers if needed.

But the biggest benefit of the test is that it can be used for internatio­nal travel for people coming back into the U.S — but you have to take it under video observatio­n by a proctor. Abbott also has a BinaxNow Home Test — versus the Self Test — that is approved for internatio­nal travel, but it’s not the one that’s available over the counter.

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