49ers (2-9) at Seahawks (6-5)
When: 1:25 p.m. TV/Radio: 2t / 680, 107.7 Spotlight on: Matt Breida: The 2017 undrafted free agent can become the first 49ers running back to rush for 100 yards in three straight games Sunday since Frank Gore did so in five straight in 2011. Breida also needs to average 52.4 yards in the final five games to become the franchise’s first 1,000-yard rusher since Gore in 2014. Seattle is 22nd in the NFL in rushing yards allowed per game (121.4). Roster report: 49ers — WRs Marquise Goodwin (personal reasons) and Pierre Garcon (shoulder, knee) are out. Seahawks — LB K.J. Wright (knee) is out.
THINGS TO WATCH
⏩ 49ers QBs have thrown for three TDs, eight interceptions and posted a 61.4 passer rating in their seven-game losing streak in Seattle.
⏩ Seahawks QB Russell Wilson has thrown for 25 TDs, five interceptions and has a career-best 112.0 passer rating this season.
⏩ Led by RB Chris Carson (635 yards), Seattle leads the NFL in rushing yards per game (147.1). The 49ers are 10th in rushing defense.
— Eric Branch