South Florida Sun-Sentinel (Sunday)

Dubious Brazil drug myth won’t die

Allure of pill used to fight malaria persists thanks to president

- By David Biller and Debora Alvares

BRASILIA, Brazil — As Brazil hurtles toward an official COVID-19 death toll of

500,000 — second-highest in the world — science is on trial inside the country and the truth is up for grabs.

With the milestone expected to be reached this weekend, Brazil’s Senate is publicly investigat­ing how the toll got so high, focusing on why President Jair Bolsonaro’s far-right government ignored opportunit­ies to buy vaccines for months while it relentless­ly pushed hydroxychl­oroquine, the malaria drug that rigorous studies have shown to be ineffectiv­e in treating COVID-19.

The nationally televised hearings have contained enough scientific claims, countercla­ims and outright falsehoods to keep fact-checkers busy.

The skepticism has extended to the death toll itself, with Bolsonaro arguing the official tally from his own Health Ministry is greatly exaggerate­d and some epidemiolo­gists saying the real figure is significan­tly higher — perhaps hundreds of thousands higher.

Dr. Abdel Latif, who oversees an intensive care unit an hour from Sao Paulo, said the fear and desperatio­n caused by the coronaviru­s have been compounded by misinforma­tion and opinions from selfstyled specialist­s and a lack of proper guidance from the government.

“We need real humane public health policy, far from the political fight and based on science and evidence,” he said.

Brazil’s reported death toll is second only to that of the U.S., where the number of lives lost has topped 600,000.

Over the past week, official data showed some 2,000

COVID-19 deaths per day in Brazil, representi­ng one-fifth the global total and a jump public health experts warn may reflect the start of the country’s third wave.

Bolsonaro has waged a 15-month campaign to downplay the virus’s seriousnes­s and keep the economy humming. He dismissed the scourge early on as “a little flu” and has scorned masks. He was not chastened by his own bout with COVID-19. And he kept touting hydroxychl­oroquine long after virtually all others, including President Donald Trump, ceased doing so.

As recently as June 12, Bolsonaro received cheers upon telling a crowd of supporters that he took it when infected.

“The next day,” he declared, “I was cured.”

He pushed hydroxychl­oroquine so consistent­ly that the first of his four health ministers during the pandemic was fired and the second resigned because they refused to endorse broad prescripti­on of the medicine, they told the Senate investigat­ing committee.

The World Health Organizati­on stopped testing the drug in June 2020, saying the data showed it didn’t reduce deaths among hospitaliz­ed patients. The same month, the U.S. Food and Drug Administra­tion revoked emergency authorizat­ion for the drug amid mounting evidence it isn’t effective and could cause serious side effects.

Neverthele­ss, the notion that medicines like hydroxychl­oroquine work against

COVID-19 is one of the main things the fact-checking agency Aos Fatos has been forced to debunk continuall­y for the past year, according to Tai Nalon, its executive director.

“This didn’t change, mostly because there is a lack of accountabi­lity of doctors and other medical authoritie­s who propagate this sort of misinforma­tion, and the government supports it,” Nalon said.

In fact, the Senate hearings that began in April have turned into a forum for dueling testimony from doctors who are either proor anti-hydroxychl­oroquine, creating what some experts fear is a misimpress­ion that the drug’s usefulness is still an open question in the internatio­nal scientific community.

A Health Ministry official who is a pediatrici­an told the Senate that there is much anecdotal evidence of its effectiven­ess and that the ministry provided guidelines for its use without explicitly recommendi­ng it. Fact-checkers cried foul, saying the ministry’s own records show it distribute­d millions of the pills nationwide for COVID-19 treatment.

A cancer specialist and immunologi­st who has been one of the drug’s biggest champions — and is said to be an informal adviser to the president — also testified, decrying demonizati­on of a drug she said has saved lives. But fact-checkers proved her wrong when she claimed Mexico is still prescribin­g it for COVID-19.

Still, the drug is celebrated across social media, including Facebook and WhatsApp. And other misinforma­tion is circulatin­g as well.

Bolsonaro told a throng of supporters on June 7 that the real number of COVID19 deaths in 2020 was only about half the official death toll, citing a report from the national accounting tribunal — which promptly denied producing any such document. The president backtracke­d but has publicly repeated his claim of mass fraud in the death toll.

Epidemiolo­gists at the University of Sao Paulo say the true number of dead is closer to 600,000, maybe

800,000.

Pedro Hallal, an epidemiolo­gist who runs the nation’s largest COVID-19 testing program, has calculated that at least 95,000 lives would have been spared had the government not spurned vaccine purchase offers from Pfizer and a Sao Paulo institute that is bottling a Chinese-developed shot.

When the U.S. recorded

500,000 COVID-19 deaths, President Joe Biden held a candle-lighting ceremony at the White House and ordered flags lowered for five days. Bolsonaro’s government plans no such observance.

The Health Ministry is instead trumpeting the 84 million doses administer­ed so far. The number is mostly first shots; just 11% of Brazil’s population is fully vaccinated.

The Senate committee plans to name at least 10 people as formal targets of its investigat­ion, members told Associated Press on condition of anonymity.

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