High troponin levels follow food poisoning
I am a 77-year-old male who apparently suffered a case of food poisoning. I say apparently because no cause was ever discovered for the uncontrollable vomiting and diarrhea that lasted for a whole day, then reoccurred briefly the following morning.
A trip to the emergency room involved many tests, but nothing turned up except a troponin level well over 0.04 ng/ml, which prompted an angiogram that didn’t reveal any problems with my heart. What else might have caused my high troponin level? -- Anon.
ANSWER: A troponin level is a standard blood test usually used to evaluate patients for heart attacks. However, newer, highly sensitive assays have proven that tiny levels of troponin may be detected in nearly everybody.
A level above 0.04 ng/ ml is often used as the cutoff for the “normal” range, but depending on the assay and population studied, a few healthy people may have levels above this. People with heart attacks may have troponin levels in the hundreds or thousands. The higher the troponin level, the more muscle damage there is.
The fact that your coronary arteries show no blockages is very good news. Other types of heart damage may also cause a high troponin level, including inflammation of the heart (myocarditis) and heart failure. Also, critical illness can cause high troponin levels (at much higher levels than you may have had) in people who don’t have heart blockages. (A median of 0.57 ng/ ml was found in people with septic shock.)
I found a long list of reported causes of elevated troponin levels, but gastroenteritis was not on the list. I suspect your body was working so hard to fight off the infection without enough fluid that your heart needed more oxygen-carrying blood than it got, leading to tiny amounts of injury to the heart muscle. You can lose a lot of fluid with vomiting and diarrhea, and people at age 77 don’t have as much reserve as used to.
DEAR DR. ROACH: I’m a 56-year-old male who never had chicken pox. When my first child was born, I had blood tests done to see if I’d ever been exposed. I had not, so I received the chicken pox vaccine in case my children exposed me. Twenty-five years later, many friends and colleagues have either received the shingles vaccine or had a shingles outbreak. My question is: Since I’ve never had chicken pox, do I still need the shingles vaccine? — D.S.S.
ANSWER: Yes, the shingles vaccine is still recommended. Shingles is a recurrence of the chicken pox virus. The vaccine you got was a live but weakened form of chicken pox. It has a lower risk of causing shingles than actual chicken pox, but there is still a risk.
Shingles is so bad that the vaccine is absolutely worth it, in my opinion. Even people who have had the old, one-shot vaccine (Zostrix), as well as those who don’t recall having had chicken pox, should get the new, two-dose vaccine (Shingrix), which is not a live virus. It’s better to just get the vaccine than get blood testing done in people who don’t recall getting chicken pox.
Dr. Roach regrets that he is unable to answer individual letters, but will incorporate them in the column whenever possible. Readers may email questions to Toyourgoodhealth@med. cornell.edu or send mail to 628 Virginia Dr., Orlando, FL 32803.