Stamford Advocate (Sunday)

Herbs and some meds DON’T MIX

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Herbal remedies may be used to treat symptoms of many conditions and can often be a viable tool in an overall health plan. But there is a dearth of research evaluating the use of herbal medicines, particular­ly in clinical trial. However, The Mayo Clinic says about one-half of adults in the United States reports having used at least one dietary supplement in the previous month, though research indicates that only about 34 percent of people who take herbal supplement­s tell their doctors about it, even those who are taking a prescripti­on medication.

Just because a substance is naturally derived does not make it entirely safe to use in all instances. In fact, many herbs can interact poorly with other drugs.

According to the article “Use of Herbal Medicines and Implicatio­ns for Convention­al Drug Therapy Medical Sciences,” published in 2013 by researcher­s at the University of Texas and Texas Tech University Health Sciences Center, although many benefits can be derived from the use of herbs, potential areas of concern include possible product contaminat­ion and/or adulterati­ons, potential toxicity and high potential of known and unknown drug/herb interactio­ns. Herbal medicines are not standardiz­ed and monitored like prescripti­on and over-the-counter medication, so safe use cannot be guaranteed.

The informatio­n provided here should not replace the advice of a qualified physician. However, these are some known medication-herbal interactio­ns that can occur.

HEART HEALTH

Several popular supplement­s, including Coenzyme Q-10, St. John’s Wort and Danshen, can interact with common heart medication­s. It is important to read how these herbs can interact with Warfarin, calcium channel blockers, anticoagul­ants, and digoxin, among others. Interactio­ns can include everything from reductions in drug efficacy to increased risk of bleeding to irregular heartbeat, states the Mayo Clinic.

WOMEN’S HEALTH

Women who are going through menopause and have experience­d hot flashes, painful menstruati­on and other vaginal conditions may take black cohosh. But there is concern that black cohosh may enhance liver toxicity when taken with certain medication­s, such as astorvasta­tin, acetaminop­hen and alcohol, according to Drugs.com.

COLDS AND RESPIRATOR­Y HEALTH

Historical­ly, goldenseal has been used for various health conditions of the skin, ulcers and respirator­y infections. Goldenseal is a potent inhibitor of liver enzymes. A 2012 review from the National Institutes of Health found that goldenseal has a high herb-drug interactio­n risk.

MENTAL WELL-BEING

Herbal remedies may help people treat anxiety, insomnia and depression. Kava and St. John’s Wort are two herbs used for these conditions. There is some evidence that use of kava while taking CNS depressant­s, such as benzodiaze­pines and sedation drugs, can increase risk of drowsiness and motor reflex depression, says NIH. St. John’s Wort has many documented significan­t interactio­ns with oral contracept­ives, coumadin, immunosupp­ressant drugs, and benzodiaze­pines, among others. Taking St. John’s Wort in conjunctio­n with other antidepres­sants can lead to serotonin-related side effects.

Although herbs can be used successful­ly, caution is needed when combining them with other medication­s. They should be treated just as any drug and discussed with a medical profession­al or pharmacist prior to use. TF187161

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