Oakland at Tennessee
What a juicy matchup to help kick off the NFL's opening week. The two best teams in the NFC, Green Bay and Seattle — sorry Atlanta, but that Super Bowl meltdown remains too strong in our minds — face off at Lambeau Field.
Unlike the AFC, where New England appears a hefty favorite, the NFC seems wide open. While clarity for a season that lasts 17 weeks isn't going to come in Week 1 — sometimes it doesn't come until December — it's fair to label the Packers and Seahawks as prime contenders.
Seattle's defense could be the league's best. Aaron Rodgers has plenty of targets on offense. Yep, a classic matchup in Week 1.
"This will fit together real well," Seahawks coach Pete Carroll says of his defense. "We should be good up front against the running game, which is always crucial to us. Then we will see how well we can build up our pass rush. I like the mix that we have."
That D will mix it up with what will be a well-balanced offense if Ty Montgomery fully makes the adjustment from receiver to starting running back.
Could this be a preview of a January NFC game?
"Well, every game could be looked at in that way, but yeah I think our two teams know," Rodgers says. "When you start the season, training camp, I'm sure 32 teams are talking about winning the Super Bowl.
"It's not really the case, so there's not that many teams that have those squads that could do it. Us and Seattle are usually in the mix. They have been and we have been for a long time. You know it's going to be two teams that expect to be there in the end."
Atlanta at Chicago
Nowhere in a medical dictionary will you find the term "Super Bowl malaise." No matter: it exists.
Will the Falcons fall victim to it? They insist not, having gotten rid of all the angst and disappointment from that collapse well before they gathered for training camp.
An offense that can beat up on anyone, particularly with running back Devonta Freeman ready to go, makes Atlanta dangerous. A defense that was somewhat suspect before it fell apart against the Patriots adds plenty of mystery to the Falcons' chances.
Oh, and you also won't find "Lake Michigan malaise" in that dictionary. But the Bears are in the midst of it.
Lots of folks point to the Titans as a team to watch, and with Derek Carr healthy, we know the Raiders are a contender. So this sets up as the best opening matchup in the AFC.
Even though it has 2016 Defensive Player of the Year Khalil Mack, Oakland must display a stingier defense, especially against the run. Tennessee, which also has uncertainty on defense, can pound the ball with DeMarco Murray and Derek Henry.
Baltimore at Cincinnati
The glory days are well behind the Ravens now, and they haven't seen the postseason since 2014 after a great run under John Harbaugh. Defense and special teams will be their calling card again.
Marvin Lewis has the second-longest tenure among NFL head coaches at 14 seasons and counting. He also has the ignominious distinction of an 0-7 playoff mark, which is unprecedented. He might need a playoff berth and a win or two to stay put.
Pittsburgh at Cleveland
One of the NFL's best (if recently lopsided) rivalries is renewed on opening weekend. The Steelers seem primed for a run toward a seventh Lombardi Trophy, though there should be at least some concern that star running back Le'Veon Bell only reported this week. Pittsburgh has the NFL's most dynamic offense, and its defense looks improved.
Make no mistake, the Browns are improved over the squad that went 1-15. Another such debacle is very unlikely, and an upset here would silence any mistake-by-thelake talk for a while.
Arizona at Detroit
Now that Matthew Stafford has become the league's highest-paid player, it's time for Detroit to use his ample skills to do more than lose in wild-card playoff games. A victory over the revitalized Cardinals would stamp the Lions as legitimate — at least in early September.
The Cardinals need a fast start after flopping early in 2016 and not being able to rally back to get a postseason berth. This roster is not that much different from the one that made the NFC title game for 2015.
Philadelphia at Washington
While Kirk Cousins makes mammoth bucks under the franchise tag and wonders where his Stafford-like long-term deal is, the Redskins must show they have upgraded their defense. It could be tested by the Eagles' upgraded receiving corps, particularly Alshon Jeffery.
There appears to be some separation in the NFC East, with Dallas and New York at the top, then these clubs. So a win even this early could be a key for Washington or Philly.
Jacksonville at Houston
After what the Houston area has been through because of Hurricane Harvey, a victory would provide some happiness. To get it, the defense that just might rival Seattle's will need to be dominant. Having J.J. Watt, noted defensive end and philanthropist, back on the field is huge.
Jacksonville will bring a tough-guy mentality to the field under coach Doug Marrone and overall boss Tom Coughlin. What the Jaguars probably don't bring is enough talent to move up much in the standings.
Carolina at San Francisco
That malaise referred to with the Falcons hit the Panthers hard last year. So did injuries. If Cam Newton can return to anything close to his MVP form and the defense is stout, especially the secondary that leaked in 2016, Carolina will be a factor in the NFC South.
While San Francisco won't push the top two in the NFC West, new coach Kyle Shanahan and general manager John Lynch have brought an aggressive approach that, in time, should pay off.
Indianapolis at Los Angeles Rams
The Luckless Colts — Andrew Luck's shoulder has not healed enough for him to play — do have some luck. After all, they open against the Rams, who are missing their best player, holdout defensive tackle Aaron Donald.
A tough game to get excited about, although Indy has Frank Gore to run the ball and L.A. has Todd Gurley.
New York Jets at Buffalo
An impossible game to get excited about. Buffalo hasn't made the playoffs since the turn of the century. New York's offseason moves might set football in Florham Park back a century.