Sun Sentinel Broward Edition

We can wipe out disease-carrying mosquitoes

- By Jim Greenwood

The Centers for Disease Control has now confirmed a link between the Zika virus and infants born with microcepha­ly, increasing the urgency of finding a cure before the height of the mosquito season. Although scientists have made significan­t progress in Zika vaccine developmen­t, final approval is years away according to the World Health Organizati­on. Destroying mosquitoes is the only viable and immediatel­y available option, with the bestway to do it starting with their DNA.

British-based biotech company Oxitec has tweaked the genes of Aedes aegypti mosquitoes, the type that carries Zika and other nasty diseases like malaria, yellow fever, dengue fever and chikunguny­a. Oxitec’s technology works to reduce the population of Aedes aegypti by geneticall­y engineerin­g them to pass on a self-limiting gene, which kills their offspring before they reach adulthood. In tests, this approach has lowered mosquito population­s by 90 percent or more.

Current mosquito interventi­ons fall short. Even with the best available methods including insecticid­e spraying, Aedes aegypti can only be reduced by about 30 percent to 50 percent, not enough to prevent the spread of disease.

Oxitec’s geneticall­y engineered mosquito is a novel approach in mosquito control because it stops the virus at the source.

Unfortunat­ely, this breakthrou­gh technology has encountere­d opposition from anti-genetic engineerin­g groups. Activists already have protested the release of the beneficial mosquitoes in Florida and a change.org petition aims to stop the technology altogether. Their reasons are mostly based on unfounded distrust of geneticall­y engineered foods.

Some activist groups also worry that decreasing population­s of mosquitoes could deprive birds, bats and fish that eat mosquitoes a major food source. Scientists say that any impact to the wildlife food chain would be minimal as these animals feed on other organisms besides mosquitoes.

Furthermor­e, the insect has been successful­ly tested in other countries, “successful­ly reducing population­s of the insect by up to 90 percent in field trials in the Cayman Islands, Brazil, Malaysia and Panama,” reported Lisa Palmer of Environmen­t 360.

We can’t afford to let unfounded fears about safe technology prevent a solution to a serious health crisis from being used.

In the United States, the Zika virus has spread with more than 50 cases being reported in14 states, including Florida where Oxitec is awaiting the Food and Drug Administra­tion’s green light to conduct trials of its mosquitoes in the Florida Keys. While the cases were all reportedly contracted by travelers, there are concerns that Zika, like dengue and chikunguny­a, could spread locally.

Let’s not wait for an epidemic to use the technology we have to protect the health of the next generation.

Jim Greenwood is president and CEO of the Biotechnol­ogy Innovation Organizati­on in Washington.

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