The Arizona Republic

BUFFALO (2-4) at INDIANAPOL­IS (1-5)

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Time, TV: 10 a.m., CBS

Line: Colts by 71⁄2

Bills’ keys: Getting RB LeSean McCoy going in the run game would take some pressure off new starting QB Derek Anderson, who played with WR Kelvin Benjamin in Carolina.

Colts’ keys: They have been an extremely pass-heavy offense and will need to find more balance with their ground game, led by RB Marlon Mack.

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