The Arizona Republic
BUFFALO (2-4) at INDIANAPOLIS (1-5)
Time, TV: 10 a.m., CBS
Line: Colts by 71⁄2
Bills’ keys: Getting RB LeSean McCoy going in the run game would take some pressure off new starting QB Derek Anderson, who played with WR Kelvin Benjamin in Carolina.
Colts’ keys: They have been an extremely pass-heavy offense and will need to find more balance with their ground game, led by RB Marlon Mack.