The Atlanta Journal-Constitution

In time of Zika, advice differs

Some experts tell women to consider avoiding pregnancy.

- Daniel G. Mcneil Jr.

As the Zika virus bears down on the United States, federal health officials are divided over a politicall­y and ethically charged question: Should they advise American women to delay pregnancy in areas where the virus is circulatin­g?

Some infectious disease experts are arguing that avoiding conception is the only sure way to prevent the births of deformed babies, according to outside researcher­s who serve on various advisory panels.

Women’s health specialist­s, on the other hand, counter that the government should not tell women what to do with their bodies. Indeed, federal health officials have never advised all the women in a region of the country to stop having children. Moreover, they say, most babies conceived during Zika epidemics in Latin America have been born healthy.

Several federal experts central to the discussion declined to be interviewe­d for this article.

Dr. Thomas R. Frieden, director of the Centers for Disease Control and Prevention, described the internal debate as “a very long conversati­on.”

For now, “we do not have a recommenda­tion to not become pregnant,” Frieden said at a “Zika summit” held recently at the CDC’s headquarte­rs in Atlanta. “We do recommend access to contracept­ion.”

Last week, the agency confirmed what many experts already believed: that the mosquito-borne virus, which is usually mild in adults, can cause severe brain damage in infants.

In view of the gathering evidence, health officials in some countries struck by Zika epidemics, including El Salvador and Colombia, have urged women to avoid pregnancy.

Dr. Marcos Espinal, who directs the Zika response of the Pan American Health Organizati­on, an arm of the World Health Organizati­on, said in an interview that he thought advising women to avoid conception during an epidemic’s relatively brief peak months, as Colombia did, “is sound advice.”

Yet the WHO does not follow that policy. Dr. Bruce Aylward, the agency’s head of emergency response, called avoiding pregnancy “a complicate­d decision that is different for each individual woman.”

Currently, the question affects Americans only in Puerto Rico, the U.S. Virgin Islands and American Samoa, where the Zika virus is circulatin­g locally.

But if the virus spreads as expected this summer, women in Hawaii and many Gulf Coast states may also be faced with tough choices.

Despite the CDC’s stance, Puerto Rico’s health secretary, Dr. Ana Ríus, has been advising women to avoid pregnancy, although she has done so in public interviews, not in a large health campaign.

Women on the island may be following her advice, she said; preliminar­y figures indicate that there are 8 percent fewer pregnancie­s than there were at this time last year.

For women living on those islands, the disease agency’s current guidelines do not advocate delaying pregnancy, instead calling the timing of conception a “deeply personal and very complex decision” and suggesting that women consult their doctors for “pregnancy planning.”

But tourists visiting the islands receive specific advice to avoid pregnancy for eight weeks after a visit, and for six months if male partners have had symptoms of Zika infection.

One expert familiar with the debate, Michael T. Osterholm, director of the University of Minnesota’s Center for Infectious Disease Research and Policy, described it as “two groups describing an elephant, one looking at the head and the other at the tail.”

Dr. William Schaffner, chairman of department of preventive medicine at Vanderbilt University Medical School, who also described the outlines of the split, said that withholdin­g conception advice might leave couples adrift.

“They have to think it through by themselves,” he said. “They may hear it from their doctors or mothers or friends at the beauty parlor, but not from the CDC.”

Advocates of delaying pregnancy give several reasons.

First, they do not believe that even the most aggressive mosquito-control efforts can protect pregnant women 24 hours a day for nine months.

No country yet has stopped dengue or chikunguny­a, which, like Zika, are spread by the Aedes aegypti mosquito, and the disease agency itself has warned that reductions of 80 to 90 percent in those mosquito population­s sometimes do not reduce disease transmissi­on.

Second, no vaccine is expected to be ready for at least two years.

Third, evidence is mounting that Zika outbreaks are intense but brief. I

Because women who recover from Zika appear to be permanentl­y immune, experts argue that delaying conception spares them the risk of having a child with severe birth defects, along with the agonizing worry — and lets them conceive safely a year later.

“It’s a no-brainer,” said Dr. Peter J. Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine. “They should say, ‘Don’t get pregnant — watch TV for six months and you won’t have a badly hurt baby.’ “

In framing the language of the guidelines, Frieden said he was “guided by the perspectiv­e” of Dr. Denise J. Jamieson, a medical officer in the CDC’s division of reproducti­ve health.

In an interview, Jamieson described birth defects as a rare complicati­on of Zika infection.

Advice from government doctors on such personal decisions, she added, “is not likely to be effective.”

Asked what advice she would have given during the last American rubella epidemic — which killed or severely handicappe­d an estimated 20,000 babies — she answered: “I would have said, ‘This is an extraordin­arily risky time to get pregnant.’”

But she does not endorse giving the same advice this time, she said, because rubella was unavoidabl­e in those prevaccine days, whereas now, “highly motivated women can take measures to avoid mosquito bites.”

 ?? SALVADOR MELENDEZ / ASSOCIATED PRESS ?? Women wait their turn for their prenatal exams at the National Hospital for Women in San Salvador, El Salvador. In the Central American nation, authoritie­s have urged women to put off pregnancy for two years after it was reported that there may be a...
SALVADOR MELENDEZ / ASSOCIATED PRESS Women wait their turn for their prenatal exams at the National Hospital for Women in San Salvador, El Salvador. In the Central American nation, authoritie­s have urged women to put off pregnancy for two years after it was reported that there may be a...

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