The Atlanta Journal-Constitution

Severity of flu season tought to predict

COVID-19 complicate­s picture, but vaccines are still best safeguard.

- By Sheldon H. Jacobson Sheldon H. Jacobson, PH.D., is a founder professor of computer science at the University of Illinois at Urbana-champaign. He applies his expertise in data-driven, riskbased assessment to evaluate and inform public policy.

Forecasts for a severe flu (influenza) season are ubiquitous. Concerns that a high rate of flu coupled with COVID-19 infections can send more people to emergency rooms and fill hospital beds at record rates. Perhaps such forecasts are not seeing the complete picture. Making forecasts with a paucity of reliable data is guaranteed to provide murky insights at best.

The 20202021 flu season never got off the ground, largely due to people physically distancing from each other and wearing face coverings. These nonmedical countermea­sures, designed to slow the spread of the coronaviru­s, were equally effective in keeping the flu in check.

Fast forward to this year, with more people out and many returning to in-person work and socializin­g, opportunit­ies to spread the flu are abundant.

The fear is that with both the coronaviru­s and the flu virus circulatin­g, a person who develops respirator­y symptoms may be unable to distinguis­h between the two. Such a convolutio­n of infections could create surges in demand on medical resources. Human nature is such that when presented with multiple options, caution urges us to select the worst-case scenario, which in this case would be COVID-19.

However, this assumes that all precaution­s to protect ourselves against COVID-19 will be abandoned, which is unlikely over the next six months.

Those most vulnerable to severe outcomes with seasonal flu are those over 65 years of age, the same group that is most vulnerable to COVID-19. This group has already been highly recep

tive to the COVID-19 vaccines, with over 94% having received at least one dose. This group will likely also get the flu vaccine with the high dose formulatio­n, hence will have protection against both viruses.

Those under 5 years of age are also vulnerable to the seasonal flu. Given that they will be ineligible for COVID-19 vaccines, having them vaccinated with the flu vaccine should be a priority.

Among those 6 to 64 years of age, getting the flu vaccine makes sense. Those in this cohort that have received the COVID-19 vaccine (those over 12 years old) will also be receptive to the flu vaccine.

Given that the U.S. government

provides a production safety net for the flu vaccine manufactur­ers, supply will not be an issue. Based on prior year supply data, around 200 million doses should be available.

Behavior is wild card

What remains unknown, the wild card for the seasonal flu, is people’s behavior.

If people abandon all physical distancing and wearing face coverings in congested public areas, then the worst-case scenario for COVID-19 and seasonal flu could occur. What will suppress the hospitaliz­ation numbers is how well people are vaccinated against both.

Given that booster COVID-19

shots are now beginning to be rolled out, will the third dose also protect more effectivel­y against infections, not just hospitaliz­ations and deaths? It is too early to assess if this will be the case, but if it turns out to be what occurs, the path forward will be smoother and swifter.

The takeaway from this analysis is that everyone can and will contribute to whether we have a mild or severe flu season. The choices that people make, and the precaution­s that people take, will determine the severity of the season. These behaviors are within each of our control.

What we cannot control is which variants of the influenza virus will circulate and be dom

inant, and will they match with the antigens selected for this year’s flu vaccines, which are set as much as nine months in advance.

Over the five flu seasons from 2015 to 2020, the flu vaccines have been between 29 and 48% effective. At such levels, their effectiven­ess reduces hospitaliz­ations and deaths.

So will this flu season be severe? It does not have to be.

 ?? ALYSSA POINTER/ALYSSA.POINTER@AJC.COM ?? Regardless of prediction­s for this season, getting the flu vaccine makes sense for all ages, and supply should not be an issue. Based on prior year supply data, around 200 million doses should be available.
ALYSSA POINTER/ALYSSA.POINTER@AJC.COM Regardless of prediction­s for this season, getting the flu vaccine makes sense for all ages, and supply should not be an issue. Based on prior year supply data, around 200 million doses should be available.
 ?? ?? Sheldon Jacobson
Sheldon Jacobson

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