The Atlanta Journal-Constitution

Mysterious hepatitis reported in Ga. children

Health department offers few details on number of cases.

- By Helena Oliviero helena.oliviero@ajc.com

The Georgia Department of Public Health said Tuesday that several cases of severe hepatitis “of an unknown origin” among young chil- dren here are under investigat­ion. They are among hundreds of unexplaine­d hepatitis cases in children reported worldwide.

During a Georgia Department of Public Health board meeting, state epidemiolo- gist Cherie Drenzek said the cases in Georgia are among a total of 109 cases reported in 25 states. DPH did not say how many children in the state are being studied for the mysterious hepatitis or whether any have died.

The cases first came to light when officials in Ala- bama contacted the Centers for Disease Control and Prevention about nine hepatitis cases among young chil- dren there in October. The CDC issued an alert, citing the nine hepatitis cases in Alabama, in late April. Since then, Drenzek said about 300 suspected cases have been reported in 24 other countries.

Nationwide, Drenzek said 90% of the children with the unidentifi­ed hepatitis were hospitaliz­ed and 14% needed organ transplant­s. Five chil- dren have died. Their median age is 2. The CDC has not provided details about the children who died or where those deaths occurred.

The DPH stressed the hepatitis is still very rare and the cause has not been determined. The CDC is looking into whether a type of adenovirus may be playing a role. About half of the children had a type of adenovirus — a common virus that causes intestinal symptoms such as vomiting and diarrhea — but none tested positive for the most commonly known hepatitis viruses.

Hepatitis is an inflammati­on of the liver that typically occurs in adults. With children, it is most commonly caused by viruses. Symptoms of hepatitis include fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, dark urine and jaundice or yellowing of the eyes or skin.

“Nationally, the CDC is casting a very wide net to try to identify affected patients and ask very detailed questions about a number of potential exposures, previous infections, other potential cofactors, toxins, medication­s, animal exposures ... you name it,” Drenzek said.

Health officials also will be looking into any possible link to coronaviru­s infections. Drenzek pointed out that the hepatitis cases are not related to COVID-19 vaccinatio­ns because these young children have not been vaccinated.

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