New Orleans (5-1) at Minnesota (4-2-1):
The Saints last week won in a “tough environment” against a playoff-caliber team at Baltimore. Now they get the Vikings, who have been spotty but lead the NFC North and are 14-3 at home vs. New Orleans.
Green Bay (3-2-1) at Los Angeles Rams (7-0):
The Packers rank fourth in passing and Aaron Rodgers has 332.8 yards passing per game and 12 touchdowns, one pick. Rams running back Todd Gurley leads the NFL with 88 points, 686 yards rushing, 144 carries and 956 yards from scrimmage. DE Aaron Donald co-leads with eight sacks.
Denver (3-4) at Kansas City (6-1):
The Chiefs have won six in a row in this series But they also rank last in yardage allowed on defense, so Denver might not be totally overmatched. Chiefs QB Patrick Mahomes leads the NFL in TD passes (22) and 25-yard-plus completions (26).
Baltimore (4-3) at Carolina (4-2):
The Panthers are home, where they’ve won eight straight. The challenge is huge against Baltimore, which fell at home by one point to New Orleans when Justin Tucker missed an extra point for the first time. That miscue shouldn’t camouflage that the Ravens lead the league in defense.
Seattle (3-3) at Detroit (3-3):
Seattle has gone physical with the run game and on defense and, despite being in retooling mode, seems ready to challenge for a wild-card playoff berth. Pete Carroll’s bunch protects the ball, too, with only six giveaways. Detroit seems to have discovered a running game: Rookie Kerryon Johnson ran for a career-high 158 yards at Miami last week.
Philadelphia (3-4) vs. Jacksonville (3-4) at London:
Coach Doug Marrone is sticking with QB Blake Bortles for now. The Eagles lead the NFL in time of possession, averaging more than 33 minutes. But with Jacksonville’s secondary under- manned, Carson Wentz could look to the air. He has thrown 173 consecutive passes without an interception.
New England (5-2) at Buffalo (2-5), Monday:
The Patriots have scored 21 or more points in the first half in each of the past four games this season to match a franchisebest streak, and the Bills have allowed 24 or more points in the first half three times.
Cleveland (2-4-1) at Pittsburgh (3-2-1):
The Browns lead the NFL with 20 takeaways, but they have scored only 31 points off those turnovers. Pittsburgh’s Ben Roethlisberger is 22-2-1 all-time against the Browns.
Washington (4-2) at New York Giants (1-6):
The New York tabloids already are projecting which quarterback the Giants will draft after they finish near the bottom of the standings. In comes surprise NFC East leader Washington, which ranks fifth in defense and has one of the top candidates for Comeback Player of the Year in Adrian Peterson.
Tampa Bay (3-3) at Cincinnati (4-3):
It’s natural to wonder about the Bengals’ psyche after again blowing a lead at home to Pittsburgh, then getting hammered in Kansas City. The Buccaneers lead the NFL in total yards per game (449.5) and yards passing per game (364).
New York Jets (3-4) at Chicago (3-3):
Chicago led the league with 18 sacks through the first four games, but has one since. Jets first-rounder Sam Darnold leads the league with 10 INTs.
Indianapolis (2-5) at Oakland (1-5):
The teardown of the roster continues in Oakland, where Jon Gruden dealt his top receiver, Amari Cooper, to Dallas. Indianapolis QB Andrew Luck seeks his fifth straight game with at least three TD passes.
San Francisco (1-6) at Arizona (1-6):
The Cardinals have won eight of the past nine in this series, including three weeks ago. San Francisco is minus-15 in turnover margin, worst in the NFL.