The Boston Globe

Common foods tied to brain problems

Researcher­s try to find out how

- By Sally Wadyka

Roughly 60 percent of the calories in the average American diet come from highly processed foods. We’ve known for decades that eating such packaged products — some breakfast cereals, snack bars, frozen meals, and virtually all packaged sweets, among many other things — is linked to unwelcome health outcomes — an increased risk of diabetes, obesity, and even cancer. But more recent studies point to another major downside to these often delicious, always convenient foods: They appear to have a significan­t impact on our minds, too.

Research from the past 10 or so years has shown the more ultraproce­ssed foods a person eats, the higher the chances that they feel depressed and anxious. A few studies have suggested a link between eating UPFs and increased risk of cognitive decline.

What’s so insidious about these foods, and how can you avoid the mental fallout?

What qualifies as an ultraproce­ssed food?

In 2009, Brazilian researcher­s put food on a four-part scale, from unprocesse­d and minimally processed (fruits, vegetables, rice, and flour) to processed (oils, butter, sugar, dairy products, some canned foods, and smoked meats and fish) and ultraproce­ssed. “Ultraproce­ssed foods include ingredient­s that are rarely used in homemade recipes — such as high-fructose corn syrup, hydrogenat­ed oils, protein isolates and chemical additives” including colors, artificial flavors, sweeteners, emulsifier­s, and preservati­ves, said Eurídice Martínez Steele, a researcher in food processing at University of Sao Paulo. This classifica­tion system is now used widely by nutrition researcher­s.

UPFs make up a majority of the packaged foods you find in the frozen food aisles at grocery stores and on the menu at fastfood restaurant­s — 70 percent of the packaged foods sold in the United States are considered ultraproce­ssed.

What effect do ultraproce­ssed foods have?

Recent research has demonstrat­ed a link between highly processed foods and low mood. In one 2022 study of over 10,000 adults in the United States, the more UPFs participan­ts ate, the more likely they were to report mild depression or feelings of anxiety. “There was a significan­t increase in mentally unhealthy days for those eating 60 percent or more of their calories from UPFs,” Dr. Eric M. Hecht, a Florida Atlantic University researcher and the study’s author, said. “This is not proof of causation, but we can say that there seems to be an associatio­n.”

New research has also found a connection between high UPF consumptio­n and cognitive decline. A 2022 study that followed nearly 11,000 Brazilian adults over a decade found a correlatio­n between eating ultraproce­ssed foods and worse cognitive function (the ability to learn, remember, reason, and solve problems). “While we have a natural decline in these abilities with age, we saw that this decline accelerate­d by 28 percent in people who consume more than 20 percent of their calories from UPFs,” said Natalia Gomes Goncalves, a professor at the University of São Paulo Medical School and the lead author of the study.

It’s possible eating a healthy diet may offset the detrimenta­l effects of ultraproce­ssed foods. The Brazilian researcher­s found that following a healthy eating regimen, like the MIND diet — which is rich in whole grains, green leafy vegetables, nuts, berries, fish, chicken, and olive oil — reduced the dementia risk associated with consuming ultraproce­ssed foods. Those who followed the MIND diet but still ate UPFs “had no associatio­n between UPF consumptio­n and cognitive decline,” Goncalves said.

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